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Physiology Synaptic Transmission
Testing
9
Physiology
Graduate
09/12/2009

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Cards

Term
Cholinergic synthesis and removal (ACh)
Definition
presynaptic terminal by cholin acetyltransferase; acetylcholinesterase in cleft
Term
Adrenergic synthesis and removal (NE and Dopamine)
Definition
presynaptic terminal; re-uptake by specific transporters
Term
Amino acid synthesis and removal (Glutamate and GABA)
Definition
presynaptic terminals; re-uptake by terminal and glial cells by specific transporters
Term
Peptide (Opioids and Substance P)
Definition
Cell body; peptidase and diffusion
Term
temporal summation
Definition
two or more quick firings at same terminal: will overcome relative refractory period
Term
spatial summation
Definition
two or more firings at different terminals to overcome threshold
Term
Presynaptic modulation
Definition
inhibition: ACh/muscarinic; activate K channels

Excitation: nicotinic; Ca flows from ECF
Term
Reciprocal inhibition
Definition
stretch receptor stimulates motor neuron of protagonist muscle while inhibiting antagonist via interneuron
Term
LTP
Definition
glutamate receptors: tetany

Ca through NMDAR and Na through NMDAR and AMPAR

Ca/protein kinases

Phosphorylation and more AMPAR

More AMPAR and more Na
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