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Psychiatric Drugs
Thought, Emotion, Behavior drugs
45
Medical
Graduate
12/14/2009

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Cards

Term
Methylphenidate
Definition
(Ex. Ritaline), a psycho-stimulant for ADHD. Blocks DA reuptake. May cause arrhythmias. Don't mix w/ TCA's.
Term
Phenelzine
Definition
An irreversible MAOI antidepressant. May cause orthostatic hypertnesion. A last drug of last resort.
Term
Tricyclic Antidepressants
Definition
TCA's block neuronal reuptake of 5HT and NE. Many side effects: sedation, weight gain, dry mouth, blurred vision, constipation, orthostatic hypertension, cardiac dysrhythmias, and death in overdose.
Term
Imipramine
Definition
A TCA. Many side effects, possible death with overdose.
Term
Amitriptyline
Definition
A TCA. Many side effects, possible death with overdose.
Term
Clomipramine
Definition
A TCA. Good for OCD.
Term
What can a TCA treat?
Definition
TCA's not only treat depression, but chronic pain, IBS, overactive bladder, ADHD, sleep apnea, narcolepsy.
Term
SSRI's
Definition
SSRI's are good for major depression, OCD, panic disorders, PTSD, bulimia, and social phobias. They are safe in overdose. May cause agitation, insomnia, or sexual dysfunction.
Term
Fluoxetine
Definition
SSRI (Prozac). Good for eating disorders
Term
Fluvoxamine
Definition
SSRI
Term
Bupropion
Definition
A selective NE reuptake inhibitor (small effect only). Antidepressant. May help to quit smoking.
Term
Chlorpromazine
Definition
A phenothiazine antipsychotic. Weak, has EPS, hypotension, weight gain, antagonist at many receptors.
Term
Fluphenazine
Definition
Stronger Phenothiazine antipsychotic. Severe EPS. D1, D2 antagonist.
Term
Phenothiazine Antipsychotics
Definition
Old class anti-psychotics. Have anti-emetic effect, but increase blood prolactin levels and have EPS side effects (acute dystonia, parkinsonism, tardive dyskinesia). Ex: Chlorpromazine and Fluphenazine
Term
Haloperidol
Definition
Antipsychotic. Also causes EPS. D2 antagonist only.
Term
Clozapine
Definition
Atypical antipsychotic. No EPS and no increase in Prolactin. May cause agranulocytosis, diabetes and seizures. Used only for refractory patients, and has some effect on negative Sx.
Term
Risperidone
Definition
Atypical antipsychotic. Causes EPS and hyperprolactinemia at higher doses.
Term
Olanzapine
Definition
Atypical antipsychotic. May cause hyperglycemia (weight gain and diabetes)
Term
Aripiprazole
Definition
Atypical antipsychotic. Partial agonist at D2 and 5HT receptors. For schizophrenia. May be useful in bipolar disorders too.
Term
Uses of antipsychotics
Definition
Antipsychotics can be used for schizophrenia, bipolar disease, Huntington's, amphetamine intoxication and intractable hiccough.
Term
Lithium
Definition
Antimanic drug. Restores manic patients to normal w/out causing sedation or behavioral depression. Blood Li levels should be checked. Nontoxic doses have no effect on normal ppl.
Term
Valproate
Definition
Antiseizure drug, good for acute episodes of mania. Fewer side effects (allopecia, weight gain) than Lithium
Term
Carbamazepine
Definition
Antiseizure drug, for people refractory to Lithium and Valproate
Term
St. Johns Wort
Definition
Not standardized or verified. Used for mild depression May increase metabolism of oral contraceptives.
Term
Electroconvulsive Therapy (ECT)
Definition
ECT is the most effective and rapid treatment for major depression. Good for pregnant women, suicidal patients, patients who don't respond to the drugs, but may cause memory loss.
Term
Venlafaxine
Definition
SNRI (Serotonin-norepinephrine uptake inhibitor. An anti-depressant.
Term
Benzodiazepines
Definition
BDZ: Fast acting anxiolytics, good for anxiety, panic and phobias. Causes less CNS depression than alcohol (can't overdose) but effects compounded by CNS depressants. Muscle relaxants, antiseizure, anterograde amnesia. Increases GABA.
Term
Diazepam
Definition
BDZ- long acting muscle relaxant.
Term
Alprazolam
Definition
Short acting BDZ, for anxiety (panic/agoraphobia)
Term
Midazolam
Definition
Short acting BDZ, pre-anesthetic only
Term
Lorazepam
Definition
BDZ, good for anxiety, anesthesia, insomnia or seizure
Term
Temazepam
Definition
BDZ, for insomnia
Term
Zolpidem
Definition
Not chemically a BDZ, but same effect. For insomnia.
Term
Buspirone
Definition
Less effective than BDZ, but used for drug addicts (if you don't want to give them valium)
Term
Flumazenil
Definition
Can reverse the effects of BDZ
Term
Disulfuram
Definition
Aldehyde dehydrogenase inhibitor (causes bad side effects w/ alcohol. Persists in systems for weeks).
Term
Naltrexone
Definition
Selective opioid antagonist
Term
Acamprosate
Definition
A GABA analog, decreases Glu transmission. Helps recovering alcoholics to stay abstinent.
Term
Naloxone
Definition
Mixed opioid agonist/antagonist, helps with alcohol abstinence.
Term
Methodone
Definition
Long half-life opioid, reduces symptoms of withdrawal.
Term
Clonidine
Definition
Alpha agonist, for hypertension. Also for ADHD and detoxification.
Term
Racemic Methylphenidate
Definition
A NDRI (norepinephrine-DA reuptake inhibitor), a CNS stimulant used for ADHD
Term
Dextroamphetamine
Definition
A potent psychostimulant for ADHD
Term
Mixed Amphetamine Salts (Adderall)
Definition
Adderall is a brand-name psychostimulant medication composed of amphetamine and dextroamphetamine, which is thought to work by increasing the amount of dopamine and norepinephrine in the brain
Term
Atomoxetine
Definition
Atomoxitine is a selective noradrenergic reuptake inhibitor. Good for ADHD
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