Term
What are drugs used to treat anxiety disorders?
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Definition
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Term
| What is the primary drug family included in the anxiolytic family? |
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Definition
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Term
| What is flunitrazepam commonly known as? |
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Definition
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Term
| What is Rohypnol prescribed use in other countries? |
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Definition
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Term
| What are some effects of Rohypnol on the body? |
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Definition
| Produces amnesia, muscle relaxation, and slowing of sychomotor performance. Sedation occurs 20-30 mins after administration of 2mg tablet and lasts about 8 hours. |
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Term
| What other drug is Rohypnol synergistic with? |
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Definition
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Term
| What are some types of Antidepressants? |
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Definition
MAO Inhibitors
Trycyclics
SSRI's
Atypical |
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Term
| What are some examples of MAO Inhibitors? |
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Definition
Parnate, Marplan, and Nardil |
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Term
| How do MAO Inhibitors work? |
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Definition
| It inhibits enzymes that break down monoamines like DA (dopamine), NE (norepinephrine), and 5HT (serotonin). |
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Term
| What are some side effects of MAO inhibitors? |
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Definition
| Fatigue, dizziness, constipation, and deadly surges in BP if taken with certain foods. |
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Term
| What are some examples of foods that require absolute restriction while someone is on MAO inhibitors? |
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Definition
| Ages cheeses; ages and cured meats; banana peel; broad bean pods; improperly stored meat, poultry, and fish; Marmite; sauerkraut; soy sauce and other soybean condiments; tap beer. |
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Term
| What are some food that require moderate restriction while someone is on MAO inhibitors? |
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Definition
| Red or white wine; bottled or canned beer (including nonalcoholic varieties). |
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Term
| How do Tricyclics work to alleviate depression? |
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Definition
| They increase the amounts of dopamine, norepinephrine, and serotonin. |
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Term
| What are some of the downfalls to Trycyclics? |
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Definition
| There is a narrow margin of safety and effectiveness. Common side effects include grogginess, headache, constipation, and weight gain. These are the "ine" drugs. |
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Term
| What are SSRI's and how do they work? |
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Definition
SSRI=Specific Serotonin Reuptake Inhibitors.
They ehnace the effect of Serotonin by blocking its reabsorption |
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Term
| How long to SSRI's take to have an effect? |
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Definition
| Typically 1-4 weeks to have an effect. |
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Term
| What are some examples of SSRI's? |
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Definition
| Prozac, Zoloft, Pacil, Celexa, and Lexipro |
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Term
| What are the benefits and side effects of SSRI's? |
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Definition
| SSRI's are safter than the older antidepressants and easier to tolerate. However, they can cause nausea, diarrhea, and decreased sexual function. |
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Term
| Desyrel (Trazodone) is an example of what type of antidepressant? |
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Definition
| An Atypical antidepressant |
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Term
| What are some examples of SNRI's? |
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Definition
| Effexor, Wellbutrin, and Pristique. |
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Term
| How do SNRI's differ from SSRI's in their mode of action? |
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Definition
| SNRI's enhance both Serotonin (5HT) and Norepinephrine (NE) |
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Term
| What is Wellbutrin called when used to treat nicotine addiction? |
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Definition
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Term
| What is it called when a person's mood swings from depression to excessive excitement? The person mayshow som eor all of the following symptoms: Aggressiveness, elation, fast urgent talking, frantic physical activity, grandiose, unrealistic ideas, and little need for sleep. |
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Definition
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Term
| What is the most common drug treatment for Manic-depression? |
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Definition
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Term
| What type of therapy diminishes the intensity of subsequent episodes of manic-depression? |
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Definition
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Term
| Treatment methods for manic-depression typically are effective within to weeks. |
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Definition
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Term
| What is the main family of drugs used as antipsychotics? |
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Definition
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Term
| What drug came to be used in the 1950's for the treatment of schizophrenia? |
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Definition
| Chloropromazine (CPZ or thorazine) |
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Term
| What is the Mechanism of Action for CPZ? |
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Definition
| It is unknown because of it's widespread and diverse effects of this class of drugs. They block NE, DA, Ach, 5HT, and histamine receptors and also have extensive actions on endocrine function. |
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Term
| What is the most promising theory revolving around the mechanism of action of phenothiazines? |
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Definition
| That it involves the transmission of information at the dopamine synapses. |
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Term
| What are the Motor Side Effects of Antipsychotics? |
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Definition
Parkinsonian Symptoms
Tardive Dyskinesia
Akathisia |
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Term
| Involuntary movements of the mouth, as well as writhing movements of the hands, truck, etc. Usually only occurs after chronic treatment and may get worse after withdrawal. Some symptoms are permanent. |
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Definition
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Term
| Difficulty in initaiting voluntary movements, muscular rigidity, stooped posture, and tremors. More likely in older patients. |
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Definition
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Term
| A compulsive reastlessness or desire to move, along with abnormal muscle sensations. More likely in younger patients. |
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Definition
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Term
| What are some Other Side Effects of Phenothiazines? |
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Definition
Photosensitivity
Orthostatic hypotension
Micellaneous- dry mouth, dilated pupils, weight gain, various hormonal abnormalitlies. Additional allergic reactions (relatively rare) include liver and blood problems. |
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Term
| Describe the side effect of Photosensitivity |
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Definition
| Skin may show rashes (an allergic reaction to light) or acquire patches of a blue-gray metallic discoloration. The eyes are even more of a problem. |
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Term
| Describe the Side Effect of Phenothiazine of Orthostatic hypotension |
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Definition
| At first the patient may get dizzy when standing up. Results from interference with the bodies circulatory system. |
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Term
| What are some examples of Phenothiazines |
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Definition
| Thorazine, Compazine, Stelazine, Prolixin, and Mellaril |
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Term
| What are some examples of Non-Phenothiazine Antipsychotics? |
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Definition
| Haldol, Navane, Loxitane, and Clozaril. |
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