Term
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Definition
Californians Like Girls in String Bikinis Corneum Lucidum Granulosum -- free nerve endings Spinosum -- Langerhans Basalis -- melanocytes, Merkel cells |
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Definition
sebacous -- holocrine!! eccrine -- sweat apocrine -- odor (axilla, groin, areaolae) |
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Term
composition of... -- zona occludens -- zona adherens -- macula adherens -- gap junction |
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Definition
tight junction -- claudins, occludins intermediate junction -- E-adherins, actin desmosome -- cadherins, intermediate filaments (i.e. keratin), desmoplakin gap -- connexon |
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Term
things in basement membrane |
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Definition
laminin, fibronectin, collagen |
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Definition
MCL, ACL, medial meniscus |
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Definition
S A ; suprascap n. I E ; suprascap n T E and adducts; axillary n S I and adducts; subscapular n |
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Definition
Some Lovers Try Positions That They Can't Handle (thumb to pinky; up to thumb to pinky)
Scaphoid Lunate T Pisiform T T Capitate Hamate |
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Term
nursemaid's elbow -- what is it, what's injured |
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Definition
radial head subluxation annular ligament is torn and displaced |
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Term
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Definition
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radial pulse disappears when moving head toward one side |
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Definition
thoracic outlet syndrome (IPSI) |
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Term
thenar and hypothenar muscles |
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Definition
OAF opposition aBduction flexion |
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Term
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Definition
obturator n (L2-4) thigh adduction medial thigh sensation |
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Term
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Definition
femoral (L2-4) thigh flexion, leg extension anterior thigh and medial leg (saphenous n.) |
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Term
trauma to lateral leg or fibula neck |
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Definition
common peroneal (L4-S2) PED -- eversion (superficial), dorsiflexion (deep) anterolateral leg and dorsal/medial foot (1st web space -- deep) |
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Term
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Definition
tibial n (L4-S2) TIP -- inversion, plantarflexion sole of foot |
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Term
posterior hip dislocation or polio |
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Definition
superior gluteal (L4-S1) -- medius, minimus thigh abduction (Trendelenburg sign -- CONTRA hip drops when standing on lesioned leg) |
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Term
posterior hip dislocation |
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Definition
inferior gluteal (L5-S2) -- maximus thigh extension, lateral rotation |
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Definition
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Term
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Definition
on cell membrane, voltage-gated |
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Term
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Definition
on SR, connected to dihydropyridine receptor |
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Term
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Definition
A band -- dArk -- myosin + actin I band -- lIght -- actin only H band -- myosin only M line -- myosin attaches Z line -- actin attaches |
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Term
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Definition
Ca binds troponin C troponin C moves tropomyosin off actin myosin can bind actin kick out Pi = power stroke bind ATP = myosin let's go |
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Term
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Definition
Ca binds calmodulin calmodlin activates MLCK phosphorylated myosin CONTRACTS
NO --> cGMP --> MLC phosphatase --> removes phosphate group from MLC --> relaxes |
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Term
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Definition
"one slow red ox" type 1 -- slow twitch, red fiber (lots of mitochondria), postural muscles |
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Term
median nerve travels between |
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Definition
flexor digitorum superficialis and profundus |
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Term
which artery travels with radial n? |
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Definition
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Term
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Definition
constitutive FGFR3 activation inhibits chondrocyte prolif!! |
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Term
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Definition
osteoporosis -- increased bone resorption type I - postmenopausal, prolactinoma --> low estrogen type II - senile normal labs |
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Term
marrow filled by primary spongiosa, Erlenmeyer flask bones |
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Definition
osteopetrosis -- decreased bone resorption nomal labs |
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Term
excessive osteoid, widened osteoid seams |
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Definition
osteomalacia/rickets -- Vit D def --> defective mineralization/calcification low Vit D --> low Ca/PO4 --> high PTH |
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Term
mosaic bone pattern, "cement lines", chalk-stick fractures |
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Definition
Paget's -- increased osteoclast activity --> increased osteoblast activity high alk phos osteogenic sarcoma!! |
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Term
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Definition
osteitis firosa cystica -- high PTH --> cystic bone spaced filled with brown fibrous tissue high PTH --> high Ca/low PO4 |
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Term
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Definition
precocious puberty polyostotic fibrous dysplasia -- bone replaced fibroblasts, collagen, irregular bony trabeculae pigmentation (cafe au lait) |
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Term
#1 determinant of bone density |
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Definition
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Term
marker of osteoblast activity |
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Definition
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Term
TRAP+, multinucleate cell |
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Definition
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Term
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Definition
RANKL, M-CSF from osteoblast OPG is RANKL decoy!! |
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Term
"double bubble" or "soap bubble" |
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Definition
osteoclastoma = giant cell tumor benign epiphyseal spindle shaped cells, giant cells! |
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Term
outgrowth of bone + cartilage cap |
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Definition
osteochondroma = exostosis benign metaphysis |
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Term
Codman's triangle, sunburst pattern |
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Definition
osteosarcoma = osteogenic sarcoma malignant metaphysis Paget's, infarcts, radiation, familial retinoblastoma -- most common primary malignant bone tumor!! |
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Term
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Definition
Ewing's sarcoma malignant diaphysis anaplastic small blue cell (chemo!) t(11;22) |
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Term
expansile glistening mass in medullary cavity |
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Definition
chondrosarcoma malignant cartilaginous tumor diaphysis |
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Term
Heberden's nodes vs. Bouchard's nodes |
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Definition
Heberden's -- DIP Bouchard's -- PIP |
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Term
which side more osteoarthritis? |
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Definition
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Term
random hydroxychloroquine side effect |
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Definition
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Term
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Definition
RA, behind knee can mimic DVT?! |
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Term
Boutonniere deformity vs. Swan-neck deformity |
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Definition
Boutonniere -- PIP up!! (tented finger) Swan-neck -- PIP down (straight-ish finger) |
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Term
RA antibodies; what type of hypersensitivity? |
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Definition
RF anti-CCP!! type III hypersensitivity |
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Term
Sjogren's vs. sicca syndrome |
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Definition
BOTH -- dry eyes, dry mouth Sjogren's -- arthritis Sicca -- dry nose/vaginal, chronic bronchitis, reflux esophagitis, NO arthritis!! |
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Term
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Definition
parotid enlargement B-cell lymphoma |
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Term
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Definition
monosodium urate -- needle-shaped, negatively birefringent -- yellow, parallel von Gierke's disease (lactic acid competes for renal excretion!!) after large meal or alcohol (alcohol metabolites compete for renal excretion!!) |
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Term
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Definition
calcium pyrophosphate -- rhomboid, positively birefringent |
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Term
positive vs. negatively birefringent |
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Definition
positive -- yellow perpendicular, blue parallel negative -- blue perpendicular, yellow parallel |
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Term
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Definition
Staph aureus, Strep, Neisseria gonorrhea (STD = Synovitis, Tenosynovitis, Dermatitis = pustules) |
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Term
sero-negative spondyloarthopathies |
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Definition
PAIR Psoriatic -- dactylitis ("sausage fingers"), "pencil-in-cup" Ankylosing spondylitis -- bamboo spine; assoc with uveitis, aortic regurg 2/2 ascending aortitis!!, peripheral enthesopathies (can ffect ostovertebral/costosternal junctions --> hypoventilation --> measure CHEST EXPANSION!!) IBD Reactive arthritis -- post-GI or chlamydia |
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Term
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Definition
F, fatigue, weight loss hilar adenopathy Raynaud's |
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Term
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Definition
erythema nodosum, Bell's palsy Schaumann (Ca and protein inclusions in giant cells) and asteroid (fireworks!) bodies uveoparotits hypercalcemia 2/2 activated macrophages |
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Term
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Definition
pain and stiffness in shoulders/hips NO weakness, normal CK temporal arteritis |
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Term
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Definition
symmetric, proximal weakness CD8+ T cell induced injury to myofibers! high CK, aldolase |
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Term
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Definition
Gottron papules (MCPs, IPs -- looks psoriasis-like) perifascicular atrophy increased malignancy risk |
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Term
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Definition
curare -- competes with ACh hemicholinium -- blocks choline reuptake --> ACh depletion |
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Term
diffuse scleroderma vs. CREST |
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Definition
diffuse -- rapid progression, early visceral involvement CREST -- more benign |
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Term
parakeratosis acanthosis spongiosis |
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Definition
parakeratosis -- hyperkeratosis with retention of nuclei acanthosis -- epidermal hyperplasia (of spinosum) spongiosis -- epidermal accum of edematous fluid in intercellular spaces |
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Definition
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Definition
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Definition
freckle -- increased melanin pigment |
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Definition
type IV hypersenstivity spongiosis histology (like early eczema!!) |
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Term
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Definition
acanthosis, parakeratosis, decreased statum granulosum Auspitz sign -- bleeding spots when scales scraped off Munro abscesses -- stratum corneum |
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Term
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Definition
pigmented epithelial prolif with keratin-filled cysts (horn cysts) "pasted on" Leser-Trelat -- a bunch suddenly = malignancy!! |
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Term
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Definition
albinism -- decreased melanin production vitiligo -- decreased melanocytes (the actual cells go away!!) |
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Term
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Definition
hyperpig associated with pregnancy or OCPs (mask of pregnancy!!) |
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Term
where is the problem? impetigo cellulitis necrotizing fasciitis SSSS |
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Definition
impetigo -- superficial cellulitis -- dermis, SQ tissue necrotizing fasciits -- deep!! SSSS -- stratum granulosum!!! |
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Term
pemphigus vulgaris vs. bullous pemphigoid |
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Definition
PV -- desmisomes, intraepidermial bullae, skin AND mucoa, + Nikolsky's sign
BP -- hemidesmisomes, subepithelial bullae, skin ONLY, - Nikolsky's sign, eosinophils!! |
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Term
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Definition
pruritis papules/vesicles on extensor surfaces; IgA deposits and microabscesses at dermal papillae |
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Term
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Definition
infection (Mycoplasma pneumo, HSV), drugs (sulfa, beta-lactams, phenytoin), cancer, auto-immune target cells; multiple forms |
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Term
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Definition
Pruritis Purple Polygonal Papules sawtooth infiltrate of lymphs hep C |
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Term
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Definition
small, rough, papules with central scale sandpaper feel cutaneous honr |
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Term
random thing associated with acanthosis nigricans |
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Definition
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Term
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Definition
inflam lesions of SQ fat! on shins fungi (coccidioidomycosis, histoplasmosis), mycobacteria (TB, leprosy), Strep, sarcoidosis |
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Term
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Definition
squamous cell carcinoma variant that grows rapidly and regresses spontaneously!! |
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Term
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Definition
dark cells with palisading nuclei |
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Term
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Definition
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Term
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Definition
prepatella -- "housemaid's knee" anserine -- medial knee; atheletes, large body habitus popliteal/gastrocnemius -- Baker's cysts |
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Term
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Definition
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Term
butt shots -- where to give, where not to give and why?! |
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Definition
good -- superolateral superomedial --> superior gluteal n. (Trendelenburg sign) inferomedial --> sciatic n. |
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Term
most rapid and complete relief of RA symtpoms |
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Definition
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Term
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Definition
superficial dermal edema, lymphatic dilation, NO epidermal changes |
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Term
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Definition
medial circumflex artery damage --> avascular necrosis (provides majority of blood to femoral head and neck) |
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Term
subperiosteal thinning of bones |
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Definition
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