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Renal 1
renal
15
Physiology
Undergraduate 3
10/06/2015

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Cards

Term
Where is ADH produced? Where is it stored?
Definition
hypothalamus
posterior pituitary
Term
What hormone will be released if blood osmality is too high?
Definition
ADH
Term
What does ADH do?
Definition
tells kidneys to retain more water to lower blood osmolality
Term
You will feel thirsty if your plasma osmolality is above what level?
Definition
295mOs/kg
Term
What happens if you are over-hydrated?
Definition
ADH secretion will decrease, signalling to the kidneys to excrete more water in the urine
Term
What is unique about brattleboro rats?
Definition
they do not produce ADH
Term
If you have excessive thirst, dilute urine, no ADH production, what condition do you suffer from?
Definition
diabetus insipidus
Term
Describe the circadian rhythm of ADH
Definition
increases at night to promote reabsorption of water, decrease urine production to reduce need to urinate while sleeping
Term
Where is water stored in the body, at the cellular level?
Definition
2/3 intracellular
1/3 extracellular
Term
What are some challenges the Arabian camel faces with hydration? (3)

How does it solve these problems? (4)
Definition
-lives in desert
-may be active in a hot, dry environment
-cannot close kidneys down to reduce urine production

Solution:
-metabolism of lipid stored in hump provides metabolic water
-can also get metabolic water from dry food
-kidneys are efficient at water recovery
-can turn off thermoregulation, increasing the core basal body temperature to prevent panting & water loss
Term
What are some hydration challenges faced by the kangaroo rat? (3)

How has the kangaroo rat adapted? (4)
Definition
-lives in arid desert
-high O2 consumption & respiratory water loss
-does not drink water
-must maintain body temperature

-water from dry good & metabolism
-underground colonies = moist air to reduce respiratory water loss
-nocturnal (avoid daytime heat)
-very dry feces
Term
Sea water is _____ dissolve salts by weight
Definition
3.5%
Term
What are some hydration challenges faced by marine mammals? (1)

How have they adapted to meet these challenges? (2)
Definition
sea water is very salty, no access to fresh water

-get water from food (krill, plankton)
-produce highly concentrated urine
Term
What hydration challenges are faced by hibernating bears?

What adaptations do they have? (5)
Definition
-do not take in any water for up to half the year (during hibernation)

-reduce body temperature (and metabolic rate)
-reduce heart rate
-lipid metabolism water balances respiratory water loss
-urea recycled to make protein
-water reabsorbed from the bladder
Term
What is the difference between a hibernating squirrels & a hibernating bear?
Definition
squirrels go to ambient BT/metabolic rate, cannot be woken up

bears go to 100-90, can be woken up!
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