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Gastrulation – a deeply conserved process in animal embryogenesis. •Involves cell movement. •Establishes early restrictions to developmental potential. •Key step in early differentiation. •Establishes the tripoblastic embryo. |
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A nuclear transplant experiment in frogs/toads that showed the cytoplasm contained factors that can control gene expression in the nucleus.
Conclusions: 1. The cytoplasm of the egg must reprogram the genetic potential of the transplanted nucleus. 2. The mechanism of restriction of potential during normal development IS NOT irreversible genetic change |
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can differentiate into any cell type or embryo |
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organism produced asexually from one ancestor to which they are genetically identical F.C STeward worked with carrot plants and found out that root cells could grow into normal adult plants |
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the growth phase of biological structures in an organisms |
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Timing of key developments stages for human embryos |
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Day 1 - Fertilisation in oviduct – cell divisions (cleavage) start. Day 4 – get to the uterus. Day 7 – ball of cells with cavity – blastocyst. Day 12 – implanted into endometrium of uterus. Week 2 – 4 nutrient directly from endometrium. Differentiation and development. Week 4 – heart starts beating. Week 5 – placenta has developed (estrogen and progesterone). End of 1st trimester most development and organogenesis complete |
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outer layer of cells. Does not contribute to embryo – only the placenta. Trophoblast secretes enzymes – breaks down molecules in endometrium. Blastocyst invades endometrium. Trophoblast proliferates into endometrium. |
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Inner cell mass form two layers – epiblast(gives rise to embryo) and hypoblast. |
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Stage after Blastula, three divisions, Ectoderm, Endoderm and Mesoderm |
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Trophoblast, Amnion, Chorion and Extra-embryonic mesoderm – placenta Yolk sac and allantois – umbilical chord. |
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All animals have tissues derived from three “germ layers”. Endoderms develop into the gut, liver, lungs. The Mesoderm develops into the skeleton, muscle, heart, kidney, blood . The Ectoderm develops into skin and nervous system. |
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