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Daily Volume of Respiratory Secretion |
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95% water 5% mucin (glycoprotein), leukocytes, salts, desquamated cells |
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- viscosity and elasticity - present at luminal surface of passageway |
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- Makes contact with cilia - Low viscosity, no elasticity |
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production of enzyme from stagnant pus (infection) |
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Clear thin frothy blood tinged sputum seen in : |
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Problems if sputum not evaluated immediately |
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- cells deform and rupture - gram -ve bacteria multiply - pH of sputum becomes more acidic |
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movement and mobilization of airway secretions |
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Ultimate goal of mucokinetic agents |
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reduce mucus gel viscosity |
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Mucolytic agent that smells/taste of rotten eggs |
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Mucolytic agent used for management of CF |
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Efficacy of Expectorant Agent |
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