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Rotation - Family Medicine - Articles 05
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Graduate
07/23/2011

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Term
What are the major adverse outcomes of Delirium in the Elderly
Definition
- prolonged hospital stay (8d longer)
- increased mortality while in hospital and in months following d/c
- increased risk of complications: hospital acquired infection, pressure ulcers, incontinence and falls)
- poor physical and cognitive recovery at 6 and 12mo w lower MMSE scores at d/c
- increased risk of placement at residential home
- increased risk of developing dementia in pts w no cognitive impairment at baseline
Term
What are the types of delirium
Definition
1) hyperactive (30%)
2) hypoactive delirium (25%)
3) mixed delirium (45%)
Term
What are the DSM-IV criteria for delirium
Definition
1) disturbance of consciousness (focus, inattention, reduced awareness)
2) change in cognition (or perceptual change, w memory deficits, disorientation, language disturbance
3) develop over hours to days and fluctuate throughout day
Term
What are the common non-correctable risk factors for delirium
Definition
1) age
- male
- mild cognitive impairment, dementia, parkinsons disease
- multiple comorbiditis: renal/hepatic disease, CVA hx, hx of falls, poor mobility, hx of prior delirium
Term
What are the major correctable factors for delirium development
Definition
- hearing impairment/visual impairment
- malnutrition, dehydration, low albumin
- social isolation, sleep deprivation, new environment, moves w/i hospital
- restraints and indwelling catheters
- new addition of three/more medication
- no time orientation
- smoking
Term
What are hte major precipitating factors for delirium
Definition
- polypharmacy
- alcohol w/d and benzodiazepines
- sepsis, shock, hypothermia
- lyte disturbance
- endocrine disturbance
- nutritional deficiencies
- cardiac, liver, or renal failure
- pulmonary disorder
- VCA/seizure
- post-sgx
- falls and fx
- anemia/GI bleed
- pain
- Ca and terminal illness
Term
A drop in what number from basline MMSE indicates delirium? A rise in what number indicates resolution of delirium?
Definition
1) 2+points
2) 3+points
Term
What are the components to the confusion assessment method?
Definition
1) acute onset and fluctuating course
2) inattention
3) disorganized thinking
4) altered mental status

*(1) and (2) required; (3) OR (4) required
Term
What is the sn and sp of the CAM for delirium
Definition
1) 94%
2) 90+%
Term
What are key components to the investigation of the delirious patient
Definition
- targeted blood tests: lytes, Cr, glucose, CBC
- u/a
- occult infection search
- EKG
- post-void residual bladder scan
- CXR
- head CT

Additional tests:
- TFT, Thyroid Ab
- drug levels
- toxicology
- B12/folate
- syphilis serology
- lumbar puncture
- EEG
- vasculitis screen including ANA and ENA
Term
What is a potential biochemical marker for delirium
Definition
- C-reactive protein (both predict incidence of delirium and recovery from it
Term
What is the prognosis for delirium at 12 mo
Definition
- 20-40% at 12mo
Term
What are clinical features of autism spectrum disorders
Definition
- lack of eye contact
- atypical language in rate, rhythm,intonation, and pronoun reversals
- sterotypy
Term
Describe seonsory processing problems in autism spectrum disorders
Definition
- touch: defensiveness vs no pain
- vision: difficulty with contrast
- auditory: loud noises very painl
- smell: may want to smell objects/intolerance to odors
- taste: picky eaters vs eating everything
Term
What is the characteristic learning method for autism spectrum disorders
Definition
1) visual learners
Term
For autism spectrum pts What is the first part of the physical exam that should be performed? What is the last part that should be performed?
Definition
1) chest
2) HEENT
Term
Define:

macule
patch
papule
plaque
nodule
tumor
Definition
1) flat lesion 0-1cm
2) flat lesion 1+cm
3) raised lesion 0-1cm
4) raised lesion 1+cm
5) palpable lesion 0-2cm within the dermis/subcutis
6) palpable lesion 2+cm within the dermis or subcutis
Term
Define: well marginated skin lesion
Definition
- transitions from normal to abnl skin within 1mm
Term
What layer of skin accumulates in hyperkeratotic skin?
Definition
- stratum corneum
Term
Define: bulla
Definition
- vesicle 1+cm in diameter
Term
Define:

telangiectasia
lichenification
excoration
fissure
purpura
Definition
1) fixed, visible dilated blood vessel within the epidermis
accentuation of normal skin lines due to persistent rubbing or scratching
- erosion/ulcer caused by scratching, rubbing, or picking
- linear split in skin through the epidermis and into the dermis
- extravasated blood in the skin (palpable)
Term
What are hte components to the ABCDE method of skin lesion ID for melanoma
Definition
1) asymmetry
- border
- color
- diameter
- evolution
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