Term
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Definition
Any molecule that binds specifically to an antibody
Any molecule bound by MHC and presented to T cells
Not necessarily an immunogen |
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Term
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Definition
Antigen that provokes and immune response
Capable of eliciting the antibody formation when introduced into a host |
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Term
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Definition
| Major Histocompatability Complex |
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Term
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Definition
Small molecules that stimulate immune response when covalently bonded to a protein
Some are controlled substances |
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Term
| Example of a hapten that is a controlled substance (2) |
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Definition
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Term
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Definition
The actual molecular structure that is bound by the Ab or Tcell receptor
aka determinant site |
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Term
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Definition
| Linear / continueous vs. Conformational/discontinuous |
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Term
| Multivalent (definition 1) |
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Definition
Most immunogens
Having more than one epitope |
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Term
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Definition
Any foreign substance
Also: self-antigens |
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Term
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Definition
| Protein that attracts Tcells to the antigens (because Tcells cannot just bind to them correctly) |
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Term
| Immunogens (definition 2) |
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Definition
Worse than antigens
ALWAYS stimulate an immune response |
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Term
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Definition
Can be conjugated to a virus/antigen to elicit immune response
NOT allowed in the US as medication because of side effects |
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Term
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Definition
| Area that the antibody "sees" as the part it is going to bind to on the antigen / immunogen |
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Term
| Multivalent (definition 2) |
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Definition
| Immunogens with several epitopes that antibodies can recognize and bind to |
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Term
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Definition
Capable of binding to an antigen
Glycoproteins |
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Term
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Definition
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Term
| Where are immunoglobulins found? |
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Definition
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Term
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Definition
Two heavy chains and two light chains held together by sulfide bnds.
Globular structures.
Between the heavy and light chains is an area that identifies the epitope. |
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Term
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Definition
On the end of the heavy & light chains
The "memory" portion for binding to antigens |
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Term
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Definition
| Each class has their own constant chain |
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Term
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Definition
| All anitbodies have different variable chains |
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Term
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Definition
| Mature B-cells that produce antibodies |
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Term
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Definition
Neutralize
Opsonization
Can NOT destroy |
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Term
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Definition
| Antibodies bind to antigen, so their binding site is taken up and they can't bind to hosts |
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Term
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Definition
Attack to antigen and flag them for destruction
They attract the killer Tcells or compliment proteins |
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