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Spleen Anatomy and Physiology
For diagnostic medical sonography students. Only study term first, then definition. More of a Q&A than term/definition.
71
Medical
Undergraduate 4
02/10/2009

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Cards

Term
The spleen is located between what two structures?
Definition
1. left hemidiaphragm 2. stomach
Term
Is the spleen intraperitoneal or retroperitoneal?
Definition
intraperitoneal
Term
What area of the spleen is not covered with peritoneum?
Definition
hilum
Term
Adult spleen length
Definition
11-12 cm
Term
Adult spleen width
Definition
7 cm
Term
Adult spleen thickness
Definition
3-4 cm
Term
Adult splenic volume index
Definition
L x W x H / 27
Term
What is a normal splenic volume index?
Definition
between 8-34
Term
Normal adult weight of the spleen
Definition
150 grams (can range from 80-300 grams)
Term
The spleen is what shape?
Definition
tetrahedral (orange segment, triangular, or ovoid)
Term
What area of the spleen is convex? concave?
Definition
superior/lateral border; medial/inferior border
Term
The spleen is the largest ____________ tissue in the body.
Definition
lymphoid
Term
The spleen is the largest part of what system in the body?
Definition
RES (reticuloendothelial system)
Term
What main function does the spleen have in utero, but ends at birth?
Definition
hematopoiesis (aka erythropoiesis)
Term
Where is the hilum located?
Definition
medial side of spleen
Term
What does the hilum contain?
Definition
splenic vein, splenic artery, lymph vessel, nerves
Term
The splenic artery is found in what location to the pancreas?
Definition
superior border
Term
The splenic artery breaks down into how many branches?
Definition
6
Term
Are the branches of the splenic artery at high risk for infarct? Why or why not?
Definition
Yes, because there aren't adequate anastomoses between the branches
Term
The splenic vein forms the portal V with what other vessel?
Definition
SMV
Term
Is the splenic vein anterior or posterior to the pancreas?
Definition
posterior
Term
The IMV can enter into what two areas?
Definition
splenic vein or junction of splenic vein and SMV
Term
What three ligaments hold the spleen in place?
Definition
1. lienorenal 2. gastrosplenic 3. phrenocolic
Term
What forms the ligaments that hold the spleen in place?
Definition
peritoneum layers that form the greater and lesser sac
Term
A subclavian abscess, splenic cyst, or left pleural effusion displaces the spleen in what direction?
Definition
caudally
Term
Loss of lung volume, left pneumonia,
paralysis of the left hemidiaphragm or large intrabdominal mass can displace the spleen in which direction?
Definition
cephalic
Term
Medial lobulation of the spleen is often confused with what?
Definition
cystic masses of the pancreatic tail
Term
True or False. The spleen is often a site of primary disease.
Definition
false
Term
Term applied to cells throughout the body that have the power to ingest certain cells.
Definition
reticuloendothelial system
Term
Name of cells that ingest other cells.
Definition
phagocytes
Term
What is phagocytosis?
Definition
breakdown of hemoglobin
Term
Iron in old blood cells is converted to ________ and is sent to bone marrow for later use in new hemoglobin.
Definition
ferritin
Term
Spleen does about _____ % of catabolic activity.
Definition
50
Term
What is red pulp composed of?
Definition
splenic sinuses and cords
Term
Where in the spleen are RBC's stored?
Definition
red pulp
Term
Tiny islands of small nodular masses of lymphoid tissue attached to arterial branches.
Definition
white pulp
Term
What are malpighian corpuscles?
Definition
small nodular masses of lymphoid tissues
Term
What organ defends the body against infection in fetal life?
Definition
liver
Term
What are the four functions of the spleen?
Definition
1. blood filtration 2. blood production 3. defense 4. reservoir
Term
Other than RBC's, what does the spleen store?
Definition
iron and metabolites
Term
Term for removing the nuclei from the RBC without destroying the cell.
Definition
pitting
Term
Term for inspection of the erythrocyte and destruction of abnormal or old ones.
Definition
culling
Term
The spleen produces RBC's in the fetus until what age?
Definition
5 months fetal life
Term
What takes over blood production sometime after birth?
Definition
bone marrow
Term
What types of cells are important for the formation of antibodies and WBC's?
Definition
lymphocytes and plasma cells
Term
What organ produces lymphocytes and plasma cells?
Definition
spleen
Term
What is the normal WBC range?
Definition
5000-10000
Term
What defines leukocytosis?
Definition
WBC levels above 20000
Term
What defines leukopenia?
Definition
WBC levels below 4000
Term
Hypersplenism, viral infection, leukemia, aplastic anemia, and diabetes have leukocytosis or leukopenia?
Definition
leukopenia
Term
Acute infection, hemorrhage, CA, and acute leukemia have leukocytosis or leukopenia?
Definition
leukocytosis
Term
Polycythemia vera and severe diarrhea will have increased or decreased RBC?
Definition
increased
Term
Acute blood loss, Hodgkin's disease, hemolytic and pernicious anemia have increased or decreased RBC?
Definition
decreased
Term
What is the lab test hematocrit?
Definition
ratio of RBC to blood volume
Term
What are normal hematocrit levels for men? women?
Definition
45-47; 42-44
Term
Blood loss will have what type of hematocrit level?
Definition
decreased
Term
Shock polycythemia vera, and severe dehydration will have what hematocrit value?
Definition
increased
Term
Splenic echogenicity to the liver.
Definition
isoechoic to hypoechoic
Term
What two things should you always identify when scanning the spleen?
Definition
left kidney and left pleural space
Term
Increased hypoechoic areas in the hilum can mimic what four things?
Definition
1. portal hypertension 2. lymphnodes 3. psuedocyst 4. pancreatic tail tumors
Term
The left liver lobe can be confused with what?
Definition
subcapsular hematoma
Term
autosplenectomy
Definition
spleen has disappeared from atrophy
Term
What is seen sonographically in wasting diseases like hemolytic anemia?
Definition
1. loss of pulp 2. increased fibrosis 3. scarring from infarcts 4. iron and calcium deposits
Term
Failure of the spleen to develop, usually associated with other anomalies
Definition
aplasia
Term
Defective development of tissue in the spleen, associated with situs inversus or cardiovascular anomalies
Definition
hypoplasia
Term
Abnormal position of the spleen, possibly from laxity of supporting ligaments
Definition
wandering spleen or ectopic
Term
dysfunctional or lax ligaments
Definition
splenic ptosis
Term
Who is more likely to have an ectopic spleen, female or male?
Definition
female
Term
What may be seen in asplenia syndrome?
Definition
two morpholigc right lungs, midline liver, IVC left of midline, horseshoe kidney, cardiac anomalies, abnormal placement of stomach.
Term
What is seen in polysplenia?
Definition
bilateral left sidedness, two morphologic left lungs, biliary atresia, GI anomalies, cardiovascular anomalies, central or left liver, multiple spleens
Term
Two other names for accessory spleens.
Definition
supernumerary spleens, splenunculus
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