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A physiologist who first described the fight or flight response. |
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A Endocrinologist that came up with the General Adaptation Syndrome. |
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Simoens, Wolff, Leshan, Engel, Friedman and Rosenman, and Simonton |
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Simoens- related evolution to psychosomatic disease
Wolff,Leshan,Engel- studied illness, disease
Friedman & Roseman- identified relationship between stress and Coronary Heart Disease
Simonton- imagery and cancer therapy |
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Stages in which our body reacts to a stimulus. Alarm Reaction, Stage of resistance, and stage of exhaustion. |
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Stress Theory (Life events theory, Hardiness theory, Social support theory) |
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Life event theory- situation requires more resources than are available
Hardiness Theory- one’s attitude toward the events determines stress
Social support theory- insufficient social support for responding to event |
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Hans Selyve's definition of Stress and stressor(Eustress and Distress) |
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Stress- The nonspecifc response of the body to any demand made upon it. (e.g., increases is BP, HR, perspiration, respiration, serum cholesterol, muscle tension)
Stressor-Any demand, stimulus, situation that requires adaptation or adjustment (traffic jam, crossing a busy street examples)
Types of stressors: Eustress- good things to which one has to adapt and that can lead to the stress response. Distress-bad things to which one has to adapt and that can lead to a stress reaction. |
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Stress reactivity(fight or flight response) Chronic and Acute Response |
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All effects are based on frequency (F), duration (D) and intensity (I) of one’s physiological reaction.
Chronic:High F and D, low I Acute: Low F and D, High I |
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Stressor Classicfications |
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Cataclysmic- disasters Personal- major lifetime events Background(major stressors)- physical/environmental, social/ organizational, interpersonal, self-talks |
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Strains what are the three types? |
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Strains are the outcomes of re-activity. Three types are Physical,Psychological, and behavioral |
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Gender differences in reactivity |
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Females: Exhibit nuturing activities and use more social groups than males.
Males: More fight or flight response |
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Goals for stress management |
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• Do not eliminate all stress • Use as a motivator for peak performance • Stress can be useful, stimulating, and welcome • Limit harmful effects |
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stress or arousal can actually increase performance |
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Relationship between stress and illness |
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The relationship between stress and illness is a complex one. Illness may result from too little stress, just as it might from too much stress. |
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Has two major components the cerebral cortex(thinking functions) and subcortex( physiological processes) |
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Includes the Limbic System (“seat of emotions”) – Thalamus – Hypothalamus |
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The hypothalamus activates the following under a stress response: – Autonomic nervous system •Immediate fight-or-flight response – Endocrine system •Short-term and long-term stress response |
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CNS – Central Nervous System – Brain and Spinal Cord
PNS – Peripheral Nervous System – Afferent System and Efferent System |
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Two systems working together during immediate stress: – Sympathetic (responsible for expending energy) – Parasympathetic (responsible for conserving energy) |
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Includes glands that secrete hormones • Hormones travel through the blood stream • These hormones change function of bodily tissues |
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Major endocrine galands and hormones |
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Hypothalamus- Epinephrine and nor epinephrine Pineal gland- melatonin Pituitary gland- Vasopressin, Oxytocin Parathyroid gland- parathyroid hormone thyroid- thyroxin thymus- thymosin adrenal gland- cortisol,adrenalin pancreas- insulin ovary- testosterone,estrogen |
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Secretes two catecholamines: epinephrine (adrenalin) and norepinephrine (noradrenalin) |
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• Influenced by the hypothalamus and pituitary gland • Adrenal cortex secretes corticoids: glucocorticoids and mineralocorticoids – Primary glucocorticoid is cortisol – Primary mineralocorticoid is aldosterone • Cortisol provides fuel for “fight-or-flight” action • Aldosterone increases blood pressure to prepare for action |
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• Influenced by the hypothalamus and pituitary gland • Thyroid gland secretes thyroxin • Increases the following: – basal metabolic rate – free fatty acids – gluconeogenesis – gastrointestinal motility – respiration – heart rate – blood pressure – anxiety |
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• Oxytocin and Vasopressin (ADH) are produced by the pituitary gland – Vasopressin acts on the kidneys to decrease urine production via water retention – Oxytocin increases contraction of the walls of blood vessels • Together, these two changes will increase blood pressure |
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The Cardiovascular system |
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• Transports blood to cells and organs • Stress on the circulatory system may cause release of oxytocin and vasopressin – Both can constrict blood vessels, leading to increased blood pressure • Heart responds with increased force of contraction • Cholesterol and free fatty acids increase risk of heart disease |
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• Responsible for digestion • Stress reduces saliva production • Increases hydrochloric acid production – Constricts blood vessels that can reduce the gastric mucus that protects the stomach lining – small fissures (ulcers) may develop in stomach lining (textbook) – Note: Stress does not cause ulcers – major cause is H. Pylori (bacterial infection) • Stress may alter rhythmic movement (peristalsis) of food, leading to bowel distress (e.g., diarrhea and constipation) and diseases (pancreatitis and irritable bowel syndrome) |
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• Stress results in tensing, known as “bracing” (often, we don’t realize we are bracing) – Term: Uptight – Common areas: back, shoulders, forehead, jaw • Leads to the development of muscle pain and aches • Types of muscle – Cardiac – Skeletal – attached to bones – Smooth – control the contraction of internal organs, blood vessel walls |
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• The stress response causes: – Increased perspiration – this increases the electrical conduction of the skin (measured by a galvanometer -- called the Galvanic Skin Response (GSR) – type of biofeedback); Can be a part of a lie detector test – Surface temperature of the skin to decrease (nor-epinephrine constricts blood vessels of the skin, e.g., colder fingers/toes, skin can appear pale due vasoconstriction) • Term – Cold feet; Nervous, stressed people described as cold, clammy, and pale • Mood rings and Stress dots (measure skin temp) |
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Psychosomatic disease involves the mind and the body; it is a real disease, not “just in the mind” (psyche for mind; soma for body) |
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What are the two types of psychosomatic disease? |
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Psychogenic-(physical disease is caused by emotional stress)
Somatogenic-(mind increases body’s susceptibility to some diseases) |
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Stress and serum cholestrol |
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Studies show that one’s perception of a stressful situation can increase serum cholesterol levels (example of the mind changing the physiology – psychogenic disease) – Tax accountants – Medical students – Military pilots – Super Bowl deaths from heart disease (increased when team lost versus won) |
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Blood Pressure (Systolic and Diastolic) |
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The amount of pressure exerted by arterial walls.
Systolic- the pressure of the blood as it leaves the heart.
Diastolic- the pressure of the blood against the arterial walls when the heart is relaxed. |
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• Excessive pressure of blood against the walls of arteries • Ruptured arteries to the heart can result in a myocardial infarction(heart attack) • Ruptured arteries to the brain can cause a cerebral hemorrhage (stroke) 90% of hypertension is termed Essential Hypertension (no known cause) |
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Contributing factors to high blood pressure |
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• Genetics • Poor diet (obesity) • Cigarette smoking • Lack of exercise • High sodium intake • Stress |
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Coronary Heart Disease (Atherosclerosis, Arteriosclerosis) |
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• Heart attacks kill more Americans than any other single cause of death
Atherosclerosis- Clogging of the arteries.
Arteriosclerosis- Loss of elasticity of the coronary arteries |
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• Cuts in the walls of the stomach or intestines • During stress, norepinephrine causes capillaries in the stomach to constrict – thus, a decrease in mucous production • As a result, hydrochloric acid eats away at the stomach lining |
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• Migraines usually last about one to two hours • More common in women than men – Decreases by age 50 (most common in 16-35 year olds) • Costs businesses more than $25 billion per year • Cause focuses on emotional stress and tension – Typical migraine sufferer is a perfectionist, ambitious, rigid, orderly, excessively competitive, and unable to delegate responsibility • Muscle relaxation training is very effective in reducing the painful effects associated with a migraine – Major problem is dilation of blood vessels to the head – Muscle relaxation increases blood flow to the periphery (arms/legs) and decreases blood flow to the head |
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• Caused by muscle tension (bracing) to such areas as the forehead, jaw, or neck • People usually take aspirin, put heat on the tense muscles, or get a massage • Muscle relaxation can be very effective for preventing tension headaches – Need to become aware of bracing and areas where you experience it |
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Mutant or abnormal cell growth resulting in a cancerous tumor |
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Allergies: Asthma, and Hayfever |
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The body’s defense against foreign substances called antigens. • When antigens enter the body – Antibodies attack by releasing chemicals – Histamine is one of these chemicals •When too many histamines are released, tissues swell, mucous increases, and air passages are constricted |
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Inflammation of a joint, possibly caused by a faulty functioning of the immune system |
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TMJ (temporomandibular) Syndrome |
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The interference with the smooth functioning of the jaw. • TMJ patients may have: – facial pain – clicking or popping sound – earaches, ringing in ears – migraine headaches – dizziness – sensitive teeth |
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Nueuropeptide Y (NPY) – molecule shown to increase angiogenesis (the growth of the blood vessels) necessary to support new tissue growth |
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Post Traumatic Stress Disorder (PTSD) |
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• PTSD results from an extreme psychological and/or physical event perceived as extremely distressing (e.g., threat to one’s life) – Most people will experience a traumatic event and up to 25% will develop PTSD |
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Stress is the result of a determination that a demand exceeds available resources • Three categories of appraisal – Primary appraisal (of the threat) – Secondary appraisal (of available resources) – Reappraisal (after attempts at coping) |
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The Model of stress (Refer to picture) |
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Life situation< Perceived as stressful< Emotional Arousal< Physiological Arousal< Consequences |
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Intervention is used to block a stressful consequence(cognitive reconstructing or medications). A roadblock (e.g., relaxation technique) between the perception phase and the emotion phase can be effective. Exercise can effectively block the continuation of stress after physiological arousal has occurred. |
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