Term
|
Definition
A) Bronchospasm via B2
B)Cardio resusitation (B1)
C)prolong duration of local anestetics and reduce blood flow (A1)
Toxicity increases arrythmia via K
Increase BP
Avoid tricyclic antidepressants, Cocaine, Beta Blockers |
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Term
|
Definition
B1 receptor agonist
Given IV, has a short T1/2
Increases Renal BF (urine)
Increase CO (+ ionotrope)
Increase a1 vascular resistance
side effects arrythima, o2 consumption increase PVR
used for cardiogenic shock, acute HF
force without rate |
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Term
|
Definition
B1 receptor agonist
positive ionotrope
B2 vasodilation of vascular smooth muscle
Increases CO, decreases vasc. resist
Same uses/side effects as dopamine
force without rate |
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Term
|
Definition
-PDE agonist (prevents cAMP breakdown)
Increase in Vasodilation
Decrease in PVR
No tolerance developes
used in acute HR
Side effects include thrombcytopenia and arrythmia |
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Term
|
Definition
B2 agonist used in treatment of asthma like problems
Also used to stop labor |
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Term
|
Definition
Cough and cold preparations and nasal decongestants via alpha 1
hypertension, BPH, ischemic heart disease, glaucoma or
hyperthyroidism should not use pseudoephedrine
elevated blood pressure,restlessness and convulsions
Children under four should not receive this drug
Children under 12 should not be given the 12 hr sustained release
preparation.
MAO-inhibitors, tricyclic
antidepressants, amphetamine or amphetamine-like |
|
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Term
| Cocaine, Amphetamine, Amphetamine-like drugs and Tricyclic antidepressants |
|
Definition
These drugs can block the synaptic transporters for norepinephrine (NET).
To varying degrees, they can also block dopamine (DAT) and serotonin (SERT)
transporters
Amphetamine and amphetamine-like drugs can also promote the release of
endogenous neurotransmitters |
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Term
|
Definition
| tricyclic antidepressants |
|
|
Term
|
Definition
It does have limited use as a local anesthetic and vasoconstrictor in specialized surgical
extremely cardiotoxic
procedures of the oral, laryngeal and nasal cavities.
This local anesthetic action is due to its ability to block Na-channels and not to effects on
monoamine transporters
euphoria is thought to be due to a blockade of
dopamine uptake (blockade of the DAT). |
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|
Term
| Adderall, Methylphenidate, Focalin (potent isomer of methyphnidate) |
|
Definition
appetite suppression
narcolepsy
ADHD |
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Term
|
Definition
b1 = equal iso/epi, low ne (heart,kidney,fat)
b2 = equal iso epi, high ne
(airways)
a1 = bv vasoconstriction
higher all esp isoproteneol
a2 = autoregultion stop release ne
little b = relax via b2, alot in constrict via alpha1 |
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