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Test 1
Intro to genetics, Mitosis and Meiosis, Chromosomes, and Sex Chromosomes
63
Science
Undergraduate 3
02/17/2016

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Term
Mitosis
Definition
Multicellular division used for growth and renewal
Term
Meiosis
Definition
Gametes, reduction of DNA content, reshuffling of genetic material
Term
Spermatogenesis
Definition
Results in 4 non-identical sperm
Term
Oorgenesis
Definition
Results in 1 egg and 2 or 3 polar bodies (depending on species)
Term
Giemsa Banding
Definition
type of black and white banding
Term
Short Arm
Definition
P arm
Term
Long Arm
Definition
Q arm
Term
Karyotype
Definition
A photomicrographic of chromosomes arranged according to a stand classification
Term
Reading Karyotypes
Definition
1. Count chrms
2. Note sex chms
3. Check for any additional or missing
4. Name it: Ex. 46XX
Term
Missing notation
Definition
45XXdel(22,7q)
Term
Absence of sex chrm
Definition
45XO
Term
Allopolyploid
Definition
Hybridization between two species
Term
Autopolyploids
Definition
Chrm duplication same species
Term
Chrm doubling
Definition
Chrm doubling wit out cytokinesis
Term
Polyploid
Definition
Extra balanced set of chrm
Term
Problems with polyploids
Definition
Have trouble during meiosis, cant go through doubling because the tetrads cant properly line up along the metaphase plate
Term
Monosomy
Definition
Missing 1 whole chrms: (2n-1)
Term
Trisomy
Definition
Triplication of 1 whole chrm: (2n+1)
Term
Deletion/ Hypoploid
Definition
Missing a little segment
Term
Duplication/ Hyperploid
Definition
Have a little extra of a segment
Term
Polytene Drosphila
Definition
Produced through 9 rounds replication without cell division
Term
Endomitosis
Definition
Chrm replication without cell division
Term
Chrm Rearrangement
Definition
Can be balanced or unbalanced
Term
Translocation
Definition
Portion of one chrm transfers to another non-homologous end
Term
Insertion
Definition
Portion transfers with in
Term
Compound Chrm
Definition
Fusion of 2 chrm arms
Term
Isochrms
Definition
Fusion of 2 chrms from same chrm
Term
Robertsonian
Definition
Fusion of 2 chrms from two different chrms joined at the centromere, usually the "p" arm
Term
Inversion
Definition
Chrm segment inverts (part flips over)
Term
Percicentric
Definition
Includes centromere in the inversion flip
Term
Paracentric
Definition
Does not include the centromere in the inversion flip
Term
Reciprocal Translocation
Definition
Chrm parts change spots no net loss of genetic material
Term
Nonreciprocal Translocation
Definition
A third copy is attached to another chrm
Term
Homozygous
Definition
Two of the same genes
Term
Heterozygous
Definition
Two different genes
Term
Wild Type
Definition
Generally "normal" phenotype
Term
Null
Definition
Makes a protein non-functional
Term
Hypomorphic
Definition
Protein has reduced function
Term
Hypermorphic
Definition
Protein has increased function
Term
Dominant Negative
Definition
non-functional protein prevents normal protein from functioning
Term
Incomplete Dominance
Definition
Heterozygote dominant does not fully mask recessive
EX: white+red=pink
Term
Codominance
Definition
Heterozygote expresses both
EX: red+yellow=orange
Term
Chi Square
Definition
((observed-expected)^2)/expected
Term
Degrees of Freedom
Definition
phenotype-1
Term
Environment-Gene Interaction
Definition
Some variation in genotype that effects phenotype
Term
Incomplete Penetrace
Definition
Same genotypes but some do not express the trait even though they have mutant allele (light switch)
Term
Variable Expressivity
Definition
Same genotype but the trait is shown nonuniformly
Term
Gene-Gene Interaction
Definition
Genes influenced in a genetic context, one gene can mask another
Term
Epistasis: Linear Pathway
Definition
Lack of functional copy of either gene, need functional copy of A&B
Term
Epistasis: Redundant Pathway
Definition
Need function from one of the two, need either protein is sufficient, A_ _ _ or
B_ _ _
Term
Pleiotropy
Definition
One gene affects many phenotypes
Term
Multigenic Trait
Definition
Many genes, one disease
Term
Principles of Segregation
Definition
Homologous and sister chromotids separate
Term
Principles of Independent Assortment
Definition
Alleles segregate during formation of gametes
Term
Principles of Dominance
Definition
One allele conceals the other
Term
Carrier
Definition
Heterozygous for trait but doesn't show it
Term
Affected
Definition
Shows trait
Term
SRY gene
Definition
Responsible for the presence of testies
Term
Dosage Compensation
Definition
The bodies way of reaching equilibrium because in females there is the double the amount of X genes
Term
Mammal Dosage Compensation
Definition
Inactivation of X-linked gene in female mammals
Term
Barr Bodies
Definition
Extra X can be visibly seen in karyotype
Term
Haplosufficiency
Definition
Recessive has negative phenotype (lethal) but on good copy can mask it
Term
Epistasis
Definition
Many genes affect one phenotype
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