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Organization (laying granulation tissue)->Granulation (new CT)->Resolution (reabsorption of exudates (debris) after repair) |
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hyperplastic scar, elevated from surface of skin due to excess scar formation; disfiguring |
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deposition by fibroblasts |
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Laying down of granulation tissue, replacement of necrotic tissue with new tissue (scar) |
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replacement by scar formation (granulation tissue) |
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replacement of lost tissue-either parenchymal or stromal |
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stomach and duodenum; typical of burn victims |
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gastric acid pepsin hypersecretion. Due to complications involving the CNS, esp the hypothalamus |
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canker sores inside mouth; resembles herpes but cause in unknown |
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Diffuse, red, non-circumscribed spreading thru tissue spaces and lymphatics. ex. Erysipelas (St. Anthony's Fire) Streptococcus pyogenes (Group A, beta hemolytic) |
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Granulomatous Inflammation |
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Definition
distinct morphologic pattern of inflammatory reaction encountered in relatively few diseases. ex. TB, Syphilis, Lymphogranuloma venereum (Chlamydia trachomatis) and certain fungal diseases |
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Granulomatous Inflammation |
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Definition
distinct morphologic pattern of inflammatory reaction encountered in relatively few diseases. ex. TB, Syphilis, Lymphogranuloma venereum and certain fungal diseases |
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characterized by formation of pseudo-membranes derived from a mixture of fibrin, dead cells, WBCs, microbes, toxins, etc. ex. Corynebacterium diptheria, Clostridium difficile |
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characterized by liquifactive necrosis associated with infection and many neutrophils ex. streptococci, staphylococci, pneumococci, gonococci, meningococci, pseudomonas |
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more severe injuries release exudates with richer protein content containing fibrinogen ex. rheumatic carditis, pneumonia, diptheria bacillus |
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mild injury evokes protein-poor exudates, ex. skin blister |
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induced by sensitivity by surgical implants, sutures,etc (breast implants) |
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Characteristic of TB, Sarcoidosis, Tularemia, etc |
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Granuloma lesion showing "horseshoe-shaped" pattern of nuclei arrangement. |
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released during inflammation; found in brain cells, mast cells and platelets, effect is vasoconstriction |
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results from extreme hypersensitivity to an allergen (ex. bee sting) -> smooth m. contraction (esp. lungs) cyanosis, and death if not corrected |
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T-Cell mediated, (ex. Mantoux TB test, Leproma skin test; poison oak, poison ivy, transplants) |
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Immediate hypersensitivity |
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antibody (IgE) dependent; mast-cell mediated; ex. ragweed, pollen, goldenrod, etc |
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Definition
a system of 9 different beta globulins, which participate and enhance Ag-Ab complexes. Also, system enhances phagocytosis of these particular Ag-Ab complexes. Considered a lytic component in Ab-Ab reactions |
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inactivation of any antigen by specific, homologous antiserum |
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forms when soluble antigen (toxins, antigenic fluids, etc) combines with homologous or specific antisera (ex. botulism toxin-anti-toxin complex) |
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Clumping of multiple particulate antigens by specific or homologous antibodies, ex. bacteria, RBCs |
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precursor to macrophages; largest of circulatory WBCs; agranulocyte |
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non-phagocytic, agranulocyte and smallest of WBCs |
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histamine and heparin-containing; has role in allergies |
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elevated in allergic reacions, ex. hay fever, no histamines; phagocytic to Ag-Ab complexes |
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Hyper-calcemia due to prolonged ingestion of milk simultaneously with alkali during peptic ulcer treatment |
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not a true neoplasia; plaques of lipid-laden macrophages; sometimes seen in diabetics, hyperlipidemia, and primary biliary cirrhosis |
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Type of embolism associated with bone crushings, particularly in chest area during resuscitation |
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type of embolism that straddles bifurcation of a vessel and blocks (ex. sits on 2 main subdivisions of pulmonary a.) |
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thrombus in vessels of calf of legs giving pain(heat and tenderness) upon dorsiflexion |
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shrinkage->contraction->recanalization |
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non-occlusive adherence to vessel or cardiac wall, but may build up to occlusive levels |
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These thrombi usually begin at site of endothelial injury or turbulence |
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This has no lines of Zahn and does not adhere to endothelium |
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exhibited by thrombus; cross section of clot shows banding or "ribbing" from layers of platelets covered with WBCs |
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lining of stomach->GB->SI->brain->kidney tubules |
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order of organ putrefaction |
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The phenomenon of recall of tissues "remembering" their previous experience |
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lesion consisting of a center of fluid material surrounded by either an immediate layer of epithelium or fibrous CT |
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a macrophage containing carbon particles in the lung is commonly called a |
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What does a venous thrombosis resulting in embolism usually affect? |
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Usually deposited on dead cells or tissues |
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refers to an accompanying pigmentation in a disease known as hemochromatosis |
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Parenchymatous repair means healing by |
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Natural response to an irritant (microbial, chemical or physical) |
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Type of cell death that occurs normally-often associated with aging or disease |
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This type of necrosis occurs most frequently in the liver |
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cell type responsible for formation of scar tissue-(several different kinds of scarring, each caused by differing amounts of collagen over expression) |
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absence of development of an organ |
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clearing of inflammation when an affected part returns to normal |
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Type of necrosis often associated with TB in which necrotic material is rich in protein in lipids |
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Special form of cell change associated with hyaline degeneration |
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What can be a sequel to whooping cough (bacterium Bordetella pertussis) |
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Thromoangiitis Obliterans (Buerger's disease) |
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Definition
Almost exclusive in young and middle age men who smoke heavily. blood vessels damaged, often severe enough to result in gangrene of extremities. |
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Where is atherosclerosis most common in? |
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The greatest number of lesions of cardiac valves result from...(Streptococcus pyogenes) |
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Chronic granulomatous infections and granulomas may be caused by what type of infection? |
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Coccidiomycosis (aka "California disease", "Desert rheumatism", "San Joaquin valley fever",and "Valley fever") is a fungal disease caused by Coccidioides immitis or C. posadasii. Endemic in certain parts of Arizona, California, Nevada, New Mexico, Texas, Utah and northwestern Mexico and it affects the |
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Psittacosis, caused by Chlamydia psittaci, primarily affects the |
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large extravascular hemorrhage forming a tumor like swelling |
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Basophilic stippling (blue-purple staining granules within the red blood cell) may indicate poison with |
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A condition (medical curiosity) in which excess lipofuscin is deposited in the colon and appendix (associated with chronic users of pigmented type cathartics ex. rhubarb) |
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Definition
In certain conditions (ex. smoking) the mucosal lining of the bronchi changes to stratified squamous epithelium. What term describes this change? |
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a factor in determining the direction of locomotion (tissue substances that summon WBCs and macrophages following injury) |
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main cell found in most cases of acute inflammation |
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Presence of vacuoles in the cytoplasm of a cell undergoing degeneration is indicative of... |
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