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test 4 lecture
chapter 12
40
Anthropology
4th Grade
04/07/2014

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Term
virus
Definition
This type of microbe cannot reproduce on its own, but instead relies on the cell that it invades to do so through protein synthesis and nucleic acid replication
Term
allergy
Definition
With this condition, the immune system over-reacts to substances that pose no threat to the body (e.g., odorant molecules from cut grass). Still the person with this condition can feel very sick when exposed to the substance.
Term
immunodeficency
Definition
Failure of the immune system to work well is called:
Term
pathogen
Definition
This name is applied to disease-causing invaders.
Term
virus
Definition
This microbe is made up of a nucleic acid strand (DNA or RNA) inside a protein shell.
Term
virus
Definition
This type of microbe is not living because it is not made up of one or more cells.
Term
Bacterium
Definition
Antibiotics are designed to target this type of pathogen.
Term
Bacterium
Definition
This common microbe is a single-celled organism that typically has a cell membrane and a cell wall.
Term
Autoimmune
Definition
When the immune system incorrectly attacks normal body cells, it is called a/an ___ disease
Term
innate
Definition
With this type of immunity, regardless of the type of antigen, a generalized immune system response will work to destroy the antigen.
Term
acquired
Definition
With this type of immunity, the response by the immune system will be targeted against that individual antigen
Term
antibodies
Definition
These proteins are secreted by B lymphocytes and bind to antigens to mark them for destruction
Term
acquired
Definition
Because each antibody is shaped to bind to only one specific antigen, it is part of this type of immunity.
Term
cytokines
Definition
These protein messengers are released by one cell and stimulate growth or activity of another cell.
Term
cytotoxic cells
Definition
Immune system cells that attack and kill cells are called:
Term
b-lymphocytes
Definition
These specific cells produce immunoglobulins.
Term
macrophages
Definition
These cells, differentiated from monocytes, are big-eaters that phagocytize bacteria and dead erythrocytes and neutrophils.
Term
neutrophils
Definition
These are the most abundant of the phagocytes.
Term
lymphocytes
Definition
These leukocytes are derived from their own stem cell line. (Fig. 16.2)
Term
dendritic cells
Definition
These star-shaped cells present antigens to and activate lymphocytes
Term
T-lymphocytes
Definition
These specific cells come in helper and killer versions
Term
lymphocytes
Definition
These leukocytes are the cells involved in acquired immunity.
Term
antigen presenting
Definition
This general type of immune system cell shows a tiny piece of a pathogen on its cell surface.
Term
eosinophils
Definition
The number of these leukocytes will be elevated in the blood during an allergic attack or when someone has parasites (e.g., worms
Term
phagocytes
Definition
Immune system cells that engulf and breakdown/digest pathogens are called:
Term
interferons
Definition
These cytokines interfere with viral replication and act as modulators of the immune response.
Term
chemotaxins
Definition
Molecules that attract phagocytes to a site of infection are called:
Term
complement
Definition
These proteins form a membrane attack complex, which creates a large pore in the membrane of a bacterium or virus-infected cell body.
Term
granzymes
Definition
These enzymes, secreted by cytotoxic T cells, destroy a cell by stimulating apoptosis.
Term
bradykinins
Definition
These molecules act as vasodilators- and they stimulate nociceptors
Term
opsonins
Definition
Proteins that coat pathogens and enhance the effectiveness of phagocytes are called:
Term
pyrogens
Definition
Molecules that affect the thermoregulatory center in the hypothalamus, leading to very high body temperatures are called:
Term
c-reactive proteins
Definition
This protein is an opsonin that activates the complement cascade. Elevated levels of this protein in the blood is a sign of inflammation, and a risk factor for cardiovascular disease
Term
perforins
Definition
These proteins, secreted by cytotoxic T-cells, form holes in the membrane of the target cell, thereby assisting in the cell’s destruction.
Term
histamine
Definition
Secreted by mast cells and basophils, these signal molecules cause vasodilation and bronchoconstriction- such as that seen during an allergic reaction.
Term
class I
Definition
A cell with this class of MHC on its surface will be destroyed by a cytotoxic T cell.
Term
class II
Definition
This class of MHC is found on antigen-presenting cells.
Term
class I
Definition
This class of MHC is found on infected body cells.
Term
class II
Definition
A cell with this class of MHC on its surface is recognized by T cells as friendly, and so will not be destroyed
Term
Major histocompatability complex
Definition
These protein complexes are used as stages to present antigens on a cell’s surface.
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