Term
What are the three functions of blood? |
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Definition
Transportation, Protection, Regulation |
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Term
What does blood transport? To where? |
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Definition
o Oxygen and Carbon dioxide transported throughout the body
o Nutrients from GI tract to tissues
o Metabolic wastes to kidneys
o Hormones from endocrine cells to target cells
o Stem cells from bone marrow to tissues where they lodge and mature
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Term
What roles does blood play in protection? |
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Definition
o Plays several roles in inflammation
§ Defense mechanism limiting spread of infection
o White blood cells destroys microbes and cancer cells
o Antibodies and complement proteins to neutralize toxins and destroy pathogens
o Platelets secrete factors that promote blood clotting and other hemostatic functions
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Term
What does blood regulate? |
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Definition
o Body temperature
Carrying heat to body surface
o Stabilize distribution of body fluids
o Buffers acids and bases
Blood proteins help stabilize pH of extracellular fluids
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Term
What is the least dense component of blood? |
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Definition
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Term
What percentage of blood is plasma? |
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Definition
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Term
What are the three main proteins that are found in plasma? |
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Definition
- Albumin
- Globulins
- Fibrinogen
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Term
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Definition
Small layer of leukocytes in a hematocrit
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Term
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Definition
The % of RBCs in the blood
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Term
Average hematocrit for females? Males? |
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Definition
- Females: 42% +/-5%
- Males: 47% +/-5%
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Term
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Definition
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Term
Where does hemopoiesis take place? |
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Definition
Occurs in red bone marrow of axial skeleton, girdles and proximal epiphysis of humerus and femur
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Term
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Definition
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Term
What stimulates RBC production? Where does it come from? |
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Definition
Erythropoietin; comes from the kidneys |
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Term
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Definition
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Term
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Definition
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Term
What is the RBC formation process? |
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Definition
1. Hemocytoblast-stem cell
2. Proerythroblast-committed cell
3. Erythroblast Early-Phase 1: Ribosome synthesis
4. Erythroblast Late-Phase 2: Hemoglobin accumulation
5. Normoblast Phase 3: Ejection of nucleus
6. Reticulocyte
7. Erythrocyte
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