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most numerous; arranged in 4-5 layers; produce keratine; protects tissues from microbes, heat and H2O loss; produce lamellar granules |
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deepest layer of epidermis; produce melanin, protective melanin to keratinocytes (are vulnerable to UV); transfer melanin to keratinocytes via cytocrine secretion |
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small fraction of epidermal cells; star shaped wandering macrophage derived from bone marrow and which infiltrate the epidermal layers and serve the immune functions of phagocytosis and antigen-presenting; easily damaged by UV radiation |
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least numerous; deepest layer resembling a spike hemisphere which communicates with the disk-like sensory terminal of a neuron; the combined structure is termed a Merkel or tactile disc they are the receptors for light or discriminative touch |
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