Term
| which of these groups is usually designated as one of the most sensitive sub-populations to exposures to toxic substances |
|
Definition
|
|
Term
| GSSG is the active (able to detoxify) configuration of glutathione |
|
Definition
False
GSSG=inactive, reduced form
GSH= active form, able to detoxify
the sulfydryl groups in GSSG bound to eachother-->cant react
|
|
|
Term
| The _____effects of chemicals usually have long latency periods (20-30 yrs) after exposure |
|
Definition
|
|
Term
| Subactue are repeated exposures |
|
Definition
True
if NOT REPEATED=acute exposures |
|
|
Term
| highly reactive susbtances produce systemic effects |
|
Definition
FALSE
highly reactive substances react or are neutralized before they have a chance to elicit a systemic response
highly reactive substances typically DONT distribute beyond their point of entry |
|
|
Term
| You need to get a substace that is highly vicious (oily). What is the best route of administration? |
|
Definition
SC- Subcutaneous
or
IM-intramuscular |
|
|
Term
Effectiveness of Routes of Exposure
(Greatest-Least) |
|
Definition
- IV- intravenous
- Inhalation
- IP-intraperiotoneal
- SC-subcutaneous
- IM-intramuscular
- Intradermal
- Oral
- Dermal
|
|
|
Term
| Together SOD and Thioredoxin neutralize free radicals |
|
Definition
FALSE
SOD and Glutathione neutralize free radicals |
|
|
Term
| The CNS is most freqeuntly involved in systemic toxicity (compared to other target organs) |
|
Definition
|
|
Term
Amygdalin is toxic because it forms a __________ after toxication. This _________ is cyanide which is highly toxic.
|
|
Definition
|
|
