Term
|
Definition
| Mimic catecholamines (Epi, NE, dopamine) |
|
|
Term
|
Definition
Cocaine
Amphetamine
Ephedrine/Pseudoephedrine
Caffeine |
|
|
Term
| Sympathomimetic signs/symptoms |
|
Definition
| "Fight or Flight" agitation, tachycardia, HTN, elevated temp, dilated pupils, DIAPHORESIS, seizures |
|
|
Term
|
Definition
| benzodiazapines (lorazipam, vallium) |
|
|
Term
|
Definition
| Acetylcholine inhibition: muscarinic and cholinergics inhibited |
|
|
Term
|
Definition
Antihistamines (diphenhydramine)- benadryl
Atropine
Jimson weed
some antipsychotics and antispasmotics
A's! |
|
|
Term
| Anticholinergic signs/symptoms |
|
Definition
Muscarinic blockade- "fight or flight runs wild"
Dry, flushed skin, NO diaphoresis (bc of blocked Ach which innervate sweat glands) |
|
|
Term
|
Definition
Benzodiazapines
Antidote: physostigmine (rarely used) |
|
|
Term
|
Definition
| Parasympathomimetic, inhibit AchE so too much Ach (PNS) |
|
|
Term
|
Definition
Organophosphates
Carbamates (fertilizer, chemical warfare)
Pilocarpine
COP |
|
|
Term
| Cholinergic signs/symptoms |
|
Definition
"Rest and Digest runs wild"
SLUDgE- Salivation, Lacrimation, Urination, Defecation, Emesis
Killer B's- Bradycardia, Bronchorrhea (watery sputum), Bronchospasm
Constricted pupils |
|
|
Term
|
Definition
Atropine (antimuscarinic)
Pralidoxime (2-PAM) -- binds to the poison |
|
|
Term
|
Definition
Narcotics (opioids) Benzodiazapines Ethanol Barbituates Clonidine
BBC |
|
|
Term
| Sedative/Hypnotic signs and symptoms |
|
Definition
Coma
RESP DEPRESSION & PINPOINT PUPILS
hypotension
bradycardia |
|
|
Term
|
Definition
Naloxone (Narcan)- opioid antidote
Flumazenil- benzo antidote |
|
|
Term
| Aspirin, Tricyclic antidepressants antidote |
|
Definition
|
|
Term
| Ethylene Glycol/Methanol antidote |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Flumazenil (rarely used- seizures) |
|
|
Term
|
Definition
| physostigmine (cause seizures, heart blocks, rarely used) |
|
|
Term
|
Definition
Uncouples ox phos
Renal Failure, Tinnitus |
|
|
