Term
| Serous cystadenocarcinoma |
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Definition
--Malignant, accounts for 50% of ovarian carcinomas
--Frequently bilateral
--Tend to have papillations/solid areas |
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Term
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Definition
--Benign, characterized by multilocular cysts
--Lined by mucous secreting columnar epithelium and filled w/ mucinous material
--May result in Pseudomyxoma peritonei |
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Term
| Mucinous cystadenocarcinoma |
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Definition
--Malignant
--Can result through rupture or metastasis in pseudomyxoma peritonei with multple peritoneal tumor implants, all producing large quantities of intraperitoneal mucinous material |
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Term
| Common themes of Surface Epithelial Tumors |
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Definition
--Clinical manifestations:Abdominal pain andAbdominal enlargement
--usually diagnoised late, and have a poor prognosis.
--Benign--easily resectable
--Malignant --Surface peritoneal spread
--Ascites common in malignancy extending beyond ovaries |
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Term
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Definition
--Resembles endometrium (could be due to endometriosis)
--USUALLY MALIGNANT |
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Term
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Definition
Psammoma bodies
Benign- columnar tubal type epithelium
LMP - increasing complexity, stratification, and atypicality
Malignant - destructive stromal invasion |
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Term
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Definition
Primarily architectural grading; nuclear atypicality can bump it up one grade
Grade I - no solid areas
Grade II - <50% solid
Grade III - >50% solid |
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Term
| Mucinous tumors--histology |
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Definition
--On histologic examination, benign mucinous tumors are characterized by a lining of tall columnar epithelial cells w/ apical mucin and the absence of cilia, akin to benign cervical or intestinal epithelia.
--Endometrioid tumors are distinguished from serous and mucinous tumors by the presence of tubular glands bearing a close resemblance to benign or malignant endometrium. |
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Term
| Clear Cell Adenocarcinoma |
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Definition
--May occur with ovarian endometrioid adenocarcinoma and endometriosis
--Solid and cystic
--Large clear cells in sheets, tubules, or cystic spaces
--Tend to be aggressive with spread beyond the ovary; poor prognosis |
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Term
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Definition
Uncommon
--Resemble urothelium
--Usually unilateral, solid and cystic
--Nests of epithelial cells within fibrous stroma
--Usually benign |
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