Shared Flashcard Set

Details

UNF Patho Workbook
Test 1 Patho workbook questions and answers. Ch 1,3,
97
Medical
Undergraduate 3
02/06/2008

Additional Medical Flashcards

 


 

Cards

Term

What are principal parts of a eukaryotic cell?

Definition
organelles
Term

T/F

The cell membrane is as a fluid mosaic.

T/F 

Proteins have a degree of mobility within the lipid bilayer.

Definition
Both senetences are true and they are relevant.
Term
What particle can penetrate cell membranes most easily?
Definition
Lipid-soluble, transport protein present
Term
In order for a cell to engage in active transport processes, it requires:
Definition

mitochondria

appropriate fuel

ATP

enzymes

(All)

Term

Which is inconsistent w/ the others?

diffusion

osmosis

filtration

phagocytosis

facilitated diffusion

Definition
phagocytosis
Term
What can transport substances "uphill" against the concentration gradient?
Definition
active transport
Term

This serves as repositories for some receptors, provides a route for transport into a cell, and relays signals into cells.

Definition
Caveolae
Term

Which are true about cytoplasm?

A. It is located outside the nucleus

B. It provides support for organelles.

C. It is mostly water.

Definition
A, B, C
Term
Anaphase
Definition
chromatid migration
Term
Chromatin
Definition
single strand of DNA, nondividing cell
Term
Metaphase
Definition

Chromatid pair alignment

Term
Mitochondria
Definition
"Generation plant" for ATP
Term
Prophase
Definition
Centriole migration
Term
Ribosome
Definition
Protein synthesis site
Term

Which are true about the retinoblastoma (RB) protein:

A. It is a brake on the progress of the cell cycle

B. Binds to gene regulatory protiens

C. Slows cell proliferation

Definition
A, B, C
Term
A major function of connective tissue is
Definition
support and binding
Term

Which are characteristics of epithelial tissue?

A. Elasticity

B. Protection

C. Fills spaces between organs

D. Secretion

Definition

B. Protection

D. Secretion

Term
What type of tissue is found in the lining of the kidney tubules?
Definition
simple cuboidal
Term

What type of tissue is found in the lining of the upper respiratory tract?

Definition
simple columnar, ciliated
Term

Signaling molecules cause all of the following except:

A. Acceleration/initiative of intracellular protein kinases.
B. Arrest of cellular growth.

C. Apoptosis

D. Conversion of an intracellular signal into an extracellular response.

Definition

D. Conversion of an intracellular signal into an extracellular response.

Term
Ligands that bind with membrane receptors include what?
Definition
hormones, antigens, neurotransmitters, drugs, and infectious agents
Term

The products from the metabolism of glucose include what?

Definition

Kilocalories

CO2

H2O

ATP

Term

Indentify the correct sequence of events for initiation and conduction of a nerve impulse.

1. Sodium moves inside

2. Potassium leaves cell

3. Sodium permeability changes

4. Resting potential is reestablished

5. Potassium permeability changes

Definition
3, 1, 5, 2, 1
Term
Increased cytoplasmic calcium
Definition
decreases permeability at the junctional complex
Term
Cell junctions:
Definition

1. coordinate activities of cells within tissues

2. hold cells together

Term
A cellular adaptation observable in uterine cervical epithelium is:
Definition
Dysplasia
Term
What are the consequences when a cell is forced into anaerobic glycolysis?
Definition

Increased lactic acid

Inadequate ATP production

Term
Hypoxia
Definition
reduced oxygen tension
Term
Contusion
Definition
bleeding in skin or underlying tissue
Term
What is the probable cause of cellular swelling in the early stages of injury?
Definition
Na-K pump fails to remove intracellular Na+
Term
A cause of asphyxiation
Definition
carbon monoxide
Term
a cause of lipid peroxidation
Definition
oxygen-derived free radicals
Term
A cause of depressed fatty acid oxidation
Definition
ethanol
Term
A cause of neurotransmitter interference
Definition
lead
Term
A cause of depressed protien synthesis
Definition
detached ribosomes
Term
Dystrophic calcification
Definition

occurs in dying or dead tissues

is observed in chronic lesions

Term
Cellular swelling is
Definition
evident early in all types of cellular injury
Term

Which is not reversible?

A. Karyolysis

B. Fatty infiltration

C. Oncosis

D. All are reversible

Definition
A. Karyolysis
Term

Aging:

A. is easy to distinguish from pathology

B. does not have a genetic relationship

C. is more advanced in primitive societies

D. None are correct

E. A, B, & C are correct

Definition
D. None are correct
Term
In aging, cross-linking implies that
Definition
cell permeability decreases
Term
This is necrosis caused by Clostridia
Definition
gas gangrene
Term
This is rigidity of muscles after somatic death
Definition
rigor mortis
Term
This is an increased number of cells
Definition
hyperplasia
Term

This is a necrosis resulting from lysosomal release

Definition
liquefactive
Term
This is a replacement of one cell type with another, more suitable type
Definition
metaplasia
Term
atrophy
Definition
decrease in cell size
Term

pancreatic necrosis causes

Definition

fatty necrosis

Term
Caseous necrosis
Definition
coagulative and liquefactive necrosis
Term
Gangrene
Definition
tissue death
Term
Apoptosis
Definition
normal and pathologic cellular self-destruction
Term

The total water loss per day in the adult is appox.?

Definition
2.8 Liters
Term
Of the 60% of the body weight made up of water, about 2/3 is:
Definition
intracellular
Term
Sodium is responsible for
Definition

ECF osmotic balance

(extracellular fluid)

Term
A milliequivalent is a unit of:
Definition
Chemical activity
Term

T/F

The positive and negative charges in blood plasma must be equal to each other.

Definition
TRUE
Term
Hydrostatic pressure
Definition
Pressure of blood within the capillaries
Term
Oncotic Pressure
Definition
water-pulling effect of plasma proteins
Term
An acid is:
Definition
a substance/chemical that donates a hydrogen ion or a proton to the solution
Term
Strong acids-
Definition

include phosphoric acid

contribute many H+ to the solution

are eliminated by the renal tubules

Term
The blood pH is maintained near 7.4 by buffering systems. The sequence from the fastest acting to the slowest acting system is:
Definition
blood buffers, lungs, kidneys
Term

The pH of saliva is about 7 and the pH of gastric guice is about 2. How many times more concentrated is the hydrogen ion in gastric juice than in saliva?

Definition
100,000
Term
Which would NOT shift the blood pH towards alkalosis?
Definition
bicarbonate ion secretion into urine
Term
Respiratory acidosis could be caused from this disease?
Definition
emphysema
Term
Respiratory alkalosis could be caused by this disease?
Definition
severe anxiety
Term
Metabolic alkalosis could be caused by this disease?
Definition
excessive baking soda ingestion
Term
What is the compensatory mechanism for respiratory acidosis?
Definition
Kidneys excrete H+ and retain HCO3-
Term
What is the compensatory mechanism for respiratory alkalosis?
Definition
Kidneys retain H+ and excrete HCO3-
Term
Phagocytosis
Definition
ingestion and destruction
Term
Specific immunity
Definition

Immunoglobulins, lymphokines

Term
Macrophage
Definition
phagocytic, agranular leukocyte of the immune system
Term
Nonspecific immunity
Definition
resistant to a large variety of antigens
Term
antigen
Definition
macromolecular pattern for antibody production
Term
Antigenicity depends on
Definition
chemical structure, foreignness, complexity
Term

The HLA complex:

Definition
antigens are found on the surfaces of most cells except erythrocytes
Term
When antigen binds to its appropriate antibody:
Definition
agglutination may occur, phagocytosis may occur, or antigen neutralization may occur
Term
Antibodies are produced by:
Definition
plasma cells
Term
An immunoglobulin contains:
Definition
two heavy and two light polypeptide chains
Term
The antibody class having the highest concentration in the blood is:
Definition
IgG
Term
This is the first antibody to challenge the antigen
Definition
IgM
Term
The primary immune response involves:
Definition
a latent period followed by peak antibody production
Term
These cells are phagocytic.
Definition
macrophages
Term
When a child develops measles and acquires an immunity to subsequent infections, the immunity is:
Definition
acquired and active
Term
What are superantigens?
Definition
increases activation signal and immune response
Term
What are epitopes?
Definition
antigenic determinants
Term
What are monoclonal antibodies?
Definition
Useful for diagnosis
Term
What are mucous membranes?
Definition
first line of defense
Term
What are memory cells?
Definition
long-term immunity
Term
These are capable of forming clones of themselves.
Definition
T & B cells
Term
These produce lymphokines
Definition
T cells
Term
These are helper and suppressor cells
Definition
T cells
Term
These form antibodies
Definition
B Cells
Term
Cell-mediated response
Definition
T cell involvement
Term
Inflammation
Definition

destroys injurious agents

confines injurious agents

stimulates and enhances immunity

promotes healing

Term

Inflammation microcirculation changes involve all of the following except:

A. Vasodilation

B. Days to develop

C. Increased vascular permeability

D. exudation of leukocytes to injury site

Definition
B. Days to develop
Term
A phagocyte's role begins w/ an inflammatory response. The sequence of phagocytosis is:
Definition
margination, diapedesis, recognition, adherence, ingestion, fusion w/ lysosomes inside the phagocyte, destruction of the target.
Term
What are local manifestations of inflammation?
Definition
swelling, pain, heat, redness
Supporting users have an ad free experience!