Term
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Definition
| the formation of plaques (atheromas) beneath the endothelium of an artery |
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Term
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Definition
| reduction in the artery’s lumen, restricted blood flow, increased blood pressure and hardening of arteries |
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Term
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Definition
| the conversion of fibrinogen into threads of fibrin |
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Term
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Definition
| a mesh that clots the blood and seals the wound, providing a scaffold for scar tissue |
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Term
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Definition
| a thrombus (clot) which has broken loose and is carried along in the blood |
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Term
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Definition
| occurs when an embolus blocks a coronary artery and may lead to myocardial infarction (heart attack) and cell death |
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Term
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Definition
| by a thrombus blocking an artery in the brain |
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Term
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Definition
| are arteries other than those found in the heart or brain |
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Term
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Definition
| is the formation of a thrombus (blood clot) in a vein (most commonly the lower leg) |
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Term
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Definition
| is a serious condition which occurs when an embolus blocks a pulmonary artery |
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Term
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Definition
| for the synthesis of steroids and is a basic component of cell membranes |
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Term
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Definition
| in the liver from saturated fats present in a normal balanced diet |
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Term
| Low Density Lipoproteins (LDL) |
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Definition
| are produced by the liver and is involved in delivering cholesterol to the cells |
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Term
| High Density Lipoproteins (HDL) |
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Definition
| transports excess cholesterol from the body cells to the liver for elimination |
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Term
| A higher ratio of HDL: LDL |
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Definition
| Is (GOOD!) important to reduce blood cholesterol levels, decreasing chances of atherosclerosis and CVD |
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Term
| Regular exercise and low fat diet leads to |
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Definition
| higher levels of HDL-cholesterol |
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Term
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Definition
| lower blood cholesterol levels by inhibiting the enzyme required to synthesise cholesterol by the liver |
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Term
| Familial hypercholesterolaemia (FH) |
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Definition
| an inherited disorder that shows an autosomal dominant pattern of inheritance eg F=dominant allele –Ff and FF=disease |
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Term
| FH sufferers has a mutated gene which |
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Definition
| affects the number or function of LDL receptors which leads to very high LDL-cholesterol levels in the blood |
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