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Unit 5
hormones,lymphatic
135
Anatomy
Not Applicable
04/05/2011

Additional Anatomy Flashcards

 


 

Cards

Term

ADH

(antidiaretic hormone)

Definition

Target: kidney

 

 

Action: keeps H2O in your body

Term

GH

(growth hormone)

Definition

Target: muscles and bones

 

Action: growth, development, remodeling

Term

TSH

(thyroid stimulating hormone)

Definition

Target: Thyroid

 

Action: stimulate T3, T4

Term

ACTH

(adrenal cortiphitrophic hormone)

Definition

Target: adrenal gland

 

Action: release stress hormone

Term

t3

(tridothyronine)

Definition

target: all cells

 

Action: regulate metabolism

Term

T4

(thyroxine)

Definition

Target: all cells

 

Action: regulate metabolism

Term
Calcitonin
Definition

Target: blood stream


Action: decreases blood calcium level, takes Ca out of blood and puts it into bones

Term

PTH

(parathyroid Hormone)

 

Definition

Target: bone cells


Action: increase blood calcium levels

Term

Epi/NEpi

(epinephrin, noraepinephrine)

Definition

Target: any cell with adrengic receptors

 

Action: continue on with sympathetic nervous system

Term
cortisol
Definition

Target: immune system, cells

 

Action: IM>supress immune system

Cells>release glucose

Term
Insulin
Definition

Target: sugar in blood stream

 

Action: decrease blood glucose levels

Term
Glucagon
Definition

Target: cells storing glucose

 

Action: increase blood glucose levels

Term
prostaglandins
Definition

Target: smooth muscles nerves, CNS

 

Action: *acts on hypatholumus to reduce fever

*causes constriction/dialation of vascular smooth muscle

*sensitizes spinal nerves to pain

Term
renin
Definition
Term
erythropoietin
Definition
Term
angiotensinogen
Definition
Term
3 functions of blood
Definition

1.transport

2.protection

3.regulation

Term
what does blood regulate?
Definition
-Ph -body temp -water content of cells
Term

what does blood transport?

 

Definition

*o2 CO2

*nutrients and wastes

*hormones

*heat

Term

males have how much blood?

Females have how much blood?

Definition

males: 4 to 5 liters

Females: 5 to 6 liters

Term
Blood Ph
Definition
7.35-7.45
Term
how much of blood is plasma?
Definition
55%
Term
how much of blood is formed elements
Definition
45%
Term
Formed elements of blood
Definition

RBC

WBC

Platelets

Term
albumins
Definition
maintain blood osmotic pressure/diffusion control across capillary walls
Term
globulins
Definition
antibodies
Term
fibrinogen
Definition
blood clotting
Term
blood plasma
Definition

*honey colored watery liquid

*transports most substances in the blood

*mostly water

Term
albumins
Definition
maintain blood asmotic pressure/diffusion control across capillary walls
Term
globulins
Definition
antibodies
Term

fibrinogen

 

Definition
blood clotting
Term
hemopoiesis
Definition
formation of blood cells
Term
erythrocytes
Definition
rbc
Term
erythrocyte functions
Definition
  • carry o2
  • carry some co2
  • regulate blood pressure
Term
Where do RBC break down in?
Definition
Spleen
Term
how many days do RBC live?
Definition
120
Term
hemoglobin
Definition

oxygen carring protien in RBC

(carries 4 O2)

Term
What part of Heme carries the O2
Definition
Iron
Term
what gives blood its red color?
Definition
Hemoglobin
Term
Erythropoiesis
Definition
RBC production
Term
RBC production happens where?
Definition
in red bone marrow
Term
Do leukocytes have a nucleus?
Definition
Yes
Term
Who's main function is to fight disease?
Definition
leukocytes
Term

leukocytosis

 

Definition
increased wbc numbers > response to stress
Term
leukopenia
Definition
decreased wbc numbers
Term
the 1st to come to trama site?
Definition
neutrophils
Term
phagocytosis
Definition
engulf large particles
Term
eutrophils function
Definition
phagocytosis
Term
2nd arrive at trama site?
Definition

monocytes

 (changes to macrophages at infection site)

Term
monobytes function
Definition
phagobytosis
Term
basophils
Definition
involved in inflammation and allergic reactions
Term
used for diagnosis's
Definition
basophils
Term
eosinophils
Definition
fight parasitic worms
Term
what is involved in reducin allergic reactions?
Definition
Eosinophils
Term
what secretes antibodies?
Definition
b cells
Term
what attacks viruses, cancer cells, transplanted organs, and are involved in transfusion reactions?
Definition
t cells
Term
these make up about 25-30% of all wbc
Definition
Lymphocytes
Term
thrombocytes functions
Definition
*for, a platlet plug(stops bleeding)
*promote clot formation
Term
Thrombosytes
Definition

cell fragments

live about 5 to 9 days

Term
MHC
Definition
cell identity markers
unique to each perosn
Term
emigration
Definition
WBC leave the blood stream. wbc roll along the endothlial cells, stick to it and squeeze through it
Term
chemotaxis
Definition
chemicals released by microbes and inflammed tissues that attrac phagocytes
Term
functions of the lymphhatic system
Definition
-drain excess interstitial fluid (3liters a day
-transport dietary lipid
-carry out immune responses
Term
the ability to ard off damage or disease through our defences
Definition
immunity or resistance
Term
2 types of immunity
Definition

innate/nonspecific

adaptive/spacific

Term
functions of the lymph
Definition

1.drain excess interstiial fluid

2. transport dietary lipid

3.carry our immune responses

Term
are lymphatic capillaris closed at one end
Definition
yes
Term
resembles veins in struckture but thinner walls, more valves
Definition
lymphatic vessels
Term
encapsulated organs with masses and B & T cells
Definition
lymph nodes
Term
how mych fluid is filtered a into the lymph vessels a day?
Definition
3L
Term
what is the most important function of lymphatic vessels
Definition
to return lost plasma proteins to blood stream
Term
2 pumps that help venous return
Definition

1. SKELETAL MUSCLE PUMP

2. RESPIRATORY PUMP

Term

*where stem cells divide and beome immunocompetent

*red bone marrow/thymus

Definition

primary lymphatic organs

 

Term

*where most immune response occurs

*lymph nodes, spleen, lymphatic nodules

Definition
secondary lyphatic organs
Term
b cells are made in...
Definition
red bone marrow
Term
t cells are made in...
Definition
thymus
Term
dendrite cells teach_____what to look for.
Definition
t cells
Term
outer cortex composed of large # of t cells
Definition
thymus
Term
immature t cells migrate here from red bone marrow where they proliferate and begin to mature
Definition
thymus
Term
clear out dead and dying cells
Definition
macrophages
Term
more mature t cells migrate here from cortex
Definition
medulla
Term
what shrinks with age 70g in infants and 3g in older adults
Definition
thymus
Term
along lymphatic vessels scattered throughout body
Definition
lymph nodes
Term
parenchyma
Definition
functional part of lymph nodes
Term
site of plasma cell and memory b cell formation
Definition
outer cortex parenchyma
Term
mainly t cells and dendrite cells
Definition

inner cortex parenchyma

 

Term
b cells, antibody producing plasma cells from cortex, macrophages
Definition
medulla of parenchyma
Term
flows through a node in 1 direction only
Definition
lymph
Term
function as filters
Definition
lymph nodes
Term
how many lymph nodes in the body
Definition
600
Term
largest single mass of lymphatic tissue in the body
Definition
spleen
Term

-lymphatic tissue (lymphocytes/macrophages)

-where b and t cells carry out immune functions

Definition
white pulp
Term

-get rid of old blood by macrophages

-store up to 1/3 of bodys platelet supply

-production of blood cells during fetal life

Definition
red pulp
Term

1st line of defense

-born with it

-both physical and chemical barriers

Definition
innate immunity
Term

2nd line of defenses

-born with it

Definition
internal defenses
Term
bacteria cant live with out
Definition
iron
Term
apoptosis
Definition
cell death
Term
4 signs of inflamation
Definition

redness

swelling

pain

heat

Term

1. vasodialation

2.emigration

3.tissue repair

Definition
3 stages of inflamation
Term
first chemical to come to trama site
Definition
chemophils
Term
monocytes becom...
Definition
macrophages
Term
what does lymphnode have that a lyphnodual doesnt have?
Definition
capsul
Term
what increases during an allergic reaction
Definition

increase basophil

increase synophil

Term
what increases during infection
Definition
increase lyphocyte
Term
% of t cells become immuno compitent
Definition
25%
Term
ability of the body to defend itself against specific invading agents
Definition
adaptive immunity
Term
substances recognized a foreign and provoking an immune response
Definition
antigens
Term
complete their development in red bone marrow
Definition
b cell
Term
migrate from red bone marrow to thymus
Definition
t cells
Term
ability to carry out adaptive immune response
Definition
immunocompetence
Term
2 types of adaptive immunity
Definition

1.cell mediated

2.antibody mediated

Term
clonal selection
Definition
lymphocyte proliferates and differentiates in response to a specific antigen
Term
effector cell
Definition
active helper t cell, active cytotoxic t cell, plasma cell, die after immne reponse
Term
memory cell
Definition
do not participate in inital immune response, respond to 2nd invasion by proliferating and differentiating into more effector and memory cells, long life span
Term
antigens have 2 characteristics
Definition

immunogenicity

reactivity

Term
reactivity
Definition
ability of antigen to react specifically with antibodes it provoked
Term
class one of MHC
Definition
build into all body cells except RBC
Term
Class 2 of MHC
Definition
only on antigen presenting cells
Term
2 ways to kill cells
Definition

1. granzymes- cause apoptosis

2.perforin- causes cytolysis(holes in membrane)

Term
memory b cells wait til microbe comes again to make antibodies
Definition
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