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VEM 5131 Veterinary Molecular Biology
Final Exam
14
Veterinary Medicine
Professional
09/30/2010

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Cards

Term
chloramphenicol
Definition
Only prokaryotes. Blocks the peptidyl transferase resctions (but can also affect organellar protein synthesis in eukaryotes)
Term
erythromycin
Definition
Only prokaryotes. Blocks translocation of peptidyl-tRNA from the A site to the P site.
Term
rifamycin
Definition
Only prokaryotes. Inhibits RNA polymerase.
Term
tetracyclines
Definition
Only prokaryotes. Blocks binding of aminoacyl-tRNA to the A site of the ribosome.
Term
anisomycin
Definition
Only eukaryotes. Blocks the peptidyl transferase reaction of cytoplasmic ribosomes.
Term
cycloheximide
Definition
Only eukaryotes. Blocks the translocation of peptidyl-tRNA from the A site to the P site.
Term
a-amanitin
Definition
Only eukaryotes. Inhibits RNA polymerase II.
Term
puromycin
Definition
Affects both proks and euks. Imitates aminoacyl-tRNA. Becomes covalently bound to the growing end of the peptide of the peptide chain to terminate translation.
Term
Actinomycin D
Definition
Affects both proks and euks. Binds to DNA, preventing transcription.
Term
histone modification: 5' acetylated H3/H4
Definition
activated
Term
histone modification: 5' trimethylated H3K4
Definition
activated
Term
histone modification: 5' trimethylated H3K9
Definition
inactivated
Term
sensitivity
Definition
TP/(TP + FN)
the ability to detect a sick animal
Term
specificity
Definition
TN/(TN + FP)
ability to ID uninfected animal
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