Term
What does MIC stand for and what does it mean? |
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Definition
Minimum Inhibitory Concentration: the minimum amount of medicine that will inhibit growth of bacteria |
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Term
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Definition
An enzyme produced by some bacteria that breaks down the beta-lactam ring in the antibiotic reducing the effectiveness |
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Term
What commonly used antibiotic has a beta-lactamase inhibitor? |
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Definition
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Term
Which penicillins can be given IV? |
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Definition
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Term
What groups of antibiotics is commonly used against rickettsial organisms? |
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Definition
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Term
What are two adverse effects of aminoglycosides? |
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Definition
1) Ototoxicity 2) Nephrotoxicity |
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Term
Name two side effects associated with fluoroquinolones? |
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Definition
1) formation of lesions in cartilage in young dogs in the rapid growth phase 2) CNS stimulation and precipitate seizures 3) retinal changes in cats resulting in blindness |
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Term
What antimicrobial is used to treat giardia? |
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Definition
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Term
What symptoms are seen in diabetic ketoacidosis? |
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Definition
Vomiting, lethargy, loss of consciousness |
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Term
What is diabetic ketoacidosis? |
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Definition
When the body cannot effectively use glucose due to insufficient insulin the body begins breaking down fats which produces ketones causing the blood to become more acidic. |
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Term
How is diabetic ketoacidosis treated? |
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Definition
IV fluids, short-acting insulin, may need to correct electrolyte imbalance |
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Term
How should insulin be handled before giving? |
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Definition
Refrigeration is recommended to extend shelf life, but not required. Roll gently between hands, do not shake. Draw up amount to be given and allow it to warm to room temperature before giving. |
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Term
Where should insulin injections be given? |
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Definition
SQ; Injection site should be moved to avoid a build up of scar tissue that will prevent proper absorption. |
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Term
How often is insulin usually administered? |
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Definition
Twice a day; every twelve hours |
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Term
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Definition
40 units of insulin per 1 ml |
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Term
What differences are there in insulin syringes? |
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Definition
U-40 syringes are designed to dose U-40 insulin and therefore the unit markings provide a different insulin dose than a U-100 syringe's same unit markings |
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Term
What hormone is given to dogs to abort litters? |
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Definition
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Term
What are the possible consequences of giving estrogen? |
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Definition
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Term
Name two symptoms of hyperthyroidism in cats. |
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Definition
1) Excessive appetite accompanied by weight loss 2) Tachycardia |
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Term
What is the name of the drug given orally to cats to drop high thyroid hormone levels? |
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Definition
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Term
What two side effects are seen in people handling prostaglandins? |
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Definition
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Term
What is the most common use for cyclosporine? What is the veterinary trade name for this product? |
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Definition
Ophthalmic ointment used to treat KCS Optimmune ointment |
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Term
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Definition
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Term
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Definition
Constriction of the pupil |
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Term
In what GI condition is metoclopramide contraindicated? |
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Definition
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Term
Why are Fleet enemas contraindicated in cats? |
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Definition
Can cause a severe electrolyte imbalance that can lead to death |
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Term
What is the action of ducosate sodium succinate? |
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Definition
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Term
What is the function of Cox-1? |
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Definition
Maintains physiologic functions like renal blood flow and synthesis of gastric mucosa. |
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Term
What is the function of Cox-2? |
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Definition
Promotes the formation of prostaglandin from cell membrane archidonic acid |
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Term
What is the benefit of NSAIDS which are selective Cox-2 inhibitors? |
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Definition
Less chance of nephrotoxicity or ulceration of the gastric mucosa |
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Term
What is the toxic effect seen in cats given acetaminophen? |
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Definition
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Term
What drug is given to counteract acetaminophen toxicity? |
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Definition
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Term
What is meant by the term teratogenic? |
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Definition
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Term
What is the name of the only NSAID labeled for use in cats in the U.S? |
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Definition
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Term
All opioid agonists are which schedule controlled substances? |
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Definition
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Term
What drug s contraindicated in a patient that has a history of seizures? |
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Definition
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Term
The behavioral drug group that is used not only to alleviate behavioral problems but also to stimulate appetite in several species of animals is? |
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Definition
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Term
A progestin, often used in the past for the treatment of inappropriate elimination in cats, that is now fallen out of favor because of serious potential side-effects including mammary hyperplasia and adenocarcinoma is? |
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Definition
Megestrol acetate (Ovaban) |
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Term
Trigger, a 5 year-old English Spaniel, has been urinating, defecating and chewing the walls of his home when his owners are away. He was recently diagnosed as having separation anxiety. What drug was prescribed? |
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Definition
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Term
The first drug of choice for a cat experiencing status epilepticus is? |
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Definition
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Term
The anticonvulsant drug that may be given rectally is? |
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Definition
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Term
Which anticonvulsant is measured in grains? |
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Definition
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Term
Griseofulvin (Fulvicin) is used in cats, dogs and horses to treat what disorder? |
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Definition
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Term
A recently reported side effect of fluroquinolone administration in cats given SID dosing at higher dosing schedule is? |
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Definition
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Term
Antimicrobial drugs like enrofloxacin (Baytril), marbofloxacin (Zeniquin) and orbofloxacin (Orbax) all belong to which group of antibiotics? |
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Definition
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Term
Julia, a 1 year-old FS boxer, was diagnosed with meningitis. The veterinarian prescribed an antibiotic that will readily pass the blood brain barrier. Which antibiotic did she prescribe? |
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Definition
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Term
Mrs. Westin brought in a kitten, recently adopted from the animal shelter, to your hospital. She noticed a patchy hair loss, which was subsequently diagnosed as ringworm infection. Which drug is most appropriate to treat this condition? |
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Definition
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Term
A very useful group of broad-spectrum drugs, whose popularity has more recently declined because of numerous potential side effects, including KCS, crystal formation, hematuria, photosensitivity and hives is the? |
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Definition
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Term
Mayzie is a 3 month old DSH who has just been diagnosed with Chlamydia psittaci. You know that Dr. Hansen will not be presribing tetracycline because? |
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Definition
It will affect the enamel on Mayzie's developing teeth |
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Term
The class of anti-infective drugs that should be avoided in all food producing animals is? |
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Definition
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Term
The most common adverse effects of aminoglycoside antimicrobials are? |
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Definition
Nephrotoxicity and ototoxicity |
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Term
Penicillins are primarily excreted by the? |
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Definition
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Term
Because of the manner in which they are excreted, tetracycline are often effective against infections of the? |
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Definition
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Term
Potentiated penicillins are? |
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Definition
Active against beta-lactamase producing bacteria |
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Term
The class of antibiotics most commonly prescribed to treat rickettsial infections is? |
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Definition
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Term
You tell the client that she should wear gloves when handling this medication because it has been associated with a rare adverse reaction in humans, aplastic anemia. Based on this information, the drug that you most likely dispensed was? |
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Definition
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Term
Which anti-infective compounds, when given to juvenile animals, can impair bone development? |
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Definition
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Term
What class of antibiotics can cause formation of lesions in articular cartilage in young dogs in the rapid growth phase? |
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Definition
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Term
A cat is given methionine to alter the pH of his urine in an effort to dissolve his struvite stones. The drug has which intended effect? |
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Definition
Acidification of the urine |
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Term
What is added to amoxicillin to make it resistant to the penicillin destroying beta-lactamase enzymes produced by some bacteria? |
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Definition
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Term
Unlike other penicillins, penicillin G is not recommended for use by mouth because... |
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Definition
It is destroyed by gastric acid |
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Term
What anticonvulsant is now being used simultaneously with phenobarbital in dogs that are non-responsive to phenobarbital alone? |
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Definition
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Term
What drug would be most effective against dermatophytes? |
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Definition
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Term
What are trimethoprim and ormetoprim? |
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Definition
Agents that enhance the bacteriocidal activity of sulfa drugs |
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Term
What effect do procaine and benzathine have on pen G? |
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Definition
They prolong absorption of penicillin G from the injection site |
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Term
Antimicrobial drugs like neomycin, gentamicin and amikacin belong to what group of antibiotics? |
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Definition
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Term
Why should tetracycline be avoided in pregnant bitches? |
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Definition
It may be deposited in dental enamel and give the pup's teeth a mottled yellow appearance |
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Term
What drug group is most likely to provoke an allergic reaction in treated animals? |
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Definition
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Term
What type of drug is acyclovir? |
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Definition
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Term
What drug is used most commonly to treat Giardia in small animals? |
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Definition
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Term
Which antibiotic commonly used in cattle has been known to cause cardiac arrest in humans who have accidentally injected it into themselves? |
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Definition
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Term
Which specific antifungal drug should be administered IV in 5% dextrose? |
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Definition
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Term
Which sulphonamide is commonly given for its anti-inflammatory effect in treating colitis? |
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Definition
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Term
Which cephalosporin is commonly given intravenously in small animals? |
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Definition
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Term
What class is the drug clindamycin (Antirobe)? |
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Definition
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Term
Why should Lincosamides not be used in horses, some laboratory animals and some chickens? |
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Definition
It causes severe GI problems such as diarrhea to the point of death |
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Term
For what type of condition is ketaconazole administered? |
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Definition
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Term
Naxcell is in what classification of antibiotic drugs? |
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Definition
3rd generation cephalosporin |
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Term
Most antidepressant drugs have their effect through inhibition of reuptake of what neurotransmitter? |
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Definition
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Term
What color do gram-positive organisms stain? |
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Definition
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Term
What color do gram-negative organisms stain? |
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Definition
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Term
What bacterium is known for its "fruity" smell? |
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Definition
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Term
What is the trade name of the drug which can be used to treat Cushings disease and canine cognitive disorder? |
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Definition
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Term
For what purpose if bethanecol administered? |
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Definition
It increases tone of the detruser muscle in urinary bladder to increase ability to empty the bladder. |
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Term
For what purpose is allopurinol administered? |
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Definition
It inhibits uric acid in the urine helping to stop formation of urate uroliths (most commonly a problem in Dalmations) |
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Term
What precautions should you take when applying DMSO to an animal's skin? |
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Definition
Wear gloves to avoid contact with the drug |
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Term
Flunixin meglamine (Banamine) is an NSAID most commonly used... |
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Definition
In horses for treatment of colic |
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Term
Glucocorticoids are often used in veterinary medicine for treatment of all of the following except... |
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Definition
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Term
T/F Glucocorticoids are generally considered safer to use than NSAID drugs |
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Definition
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Term
What NSAID is used cautiously in cats with cardiomyopathy to prevent thromboembolism? |
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Definition
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Term
An opioid analgesic often used in transdermal patches to control postsurgical pain is... |
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Definition
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Term
The H2 receptors are found in the? |
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Definition
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Term
Short-term effects of corticosteroid therapy include all of the following, except? |
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Definition
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Term
Histamine is released from... |
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Definition
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Term
Which opioid in an agonist/antagonist? |
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Definition
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Term
Pain receptors are called? |
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Definition
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Term
Parenteral administration of phenylbutazone should only be via... |
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Definition
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Term
In dogs that have been receiving long-term glucocorticoid therapy, what endocrinopathies can occur? |
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Definition
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Term
What clinical signs may indicate that an animal is experiencing lidocaine toxicity? |
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Definition
CNS signs: Drowsiness, ataxia, muscle tremors |
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Term
What drug provides analgesic relief to a patient undergoing a painful procedure? |
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Definition
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Term
The most common side effect of NSAIDs are? |
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Definition
GI ulceration and hemorrhage |
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Term
What type of nerve fiber carries sharp pricking pain? |
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Definition
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Term
Chronic burning pain is carried by what type of nerve fibers? |
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Definition
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Term
Two NSAIDs used frequently in dogs for the relief of pain and inflammation, especially that associated with osteoarthritis, are |
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Definition
Carprofen (Rimadyl) and etodolac (Etogesic) |
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Term
The species that best tolerates the side effects of NSAIDs is |
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Definition
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Term
The adrenal cortex is made up of the... |
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Definition
Zona glomerulosa Zona fasciculata Zona reticularis |
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Term
What NSAID is administered to cats with a dosing interval of 2 days or more? |
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Definition
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Term
A common side effect of antihistamine drugs such as diphenhydramine is? |
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Definition
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Term
Chronic use of moderate to high doses of glucocorticoids may result in the development of? |
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Definition
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Term
The species that generally clears NSAIDs most slowly is? |
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Definition
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Term
In dogs that have been receiving long-term glucocorticoid therapy, a sudden discontinuation of the drug may result in what medical problem? |
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Definition
Iatrogenic addisionian crisis |
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Term
The glucocorticoid drug commonly used orally to treat inflammatory conditions in dogs and cats is... |
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Definition
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Term
In what species might glucocorticoid administration lead to abortion during the last few weeks of gestation? |
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Definition
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Term
Predictable, short-term effects of glucocorticoid therapy of which every client should be aware are? |
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Definition
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Term
What are the effects of glucocorticoid use on the CBC? |
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Definition
Neutrophils increased Eosinophils decreased Lymphocytes decreased |
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Term
Dogs with heartworm disease are treated with aspirin because it... |
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Definition
Decreases the risk of clot formation and proliferation of the pulmonary arterial lining |
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Term
What topical anti-inflammatory should only be applied to a clean area because it readily penetrates the skin and can carry bacterial toxins or other chemicals with it into the body is? |
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Definition
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Term
What is iatrogenic Cushings? |
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Definition
Long-term use of steroids means increased cortisol in the body which leads to Cushings |
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Term
Give three clinical signs of the disease? |
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Definition
1) Thin skin 2) Muscle wasting 3) Distended abdomen |
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Term
What was the original use of DMSO prior to its use in medicine? |
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Definition
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|
Term
What is DMSO typically used for now? |
|
Definition
An anti-inflammatory agent and to carry drugs through the skin |
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Term
Why is epinephrine added to lidocaine when it is used as a local anesthetic? |
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Definition
It causes vasoconstriction which keeps the lidocaine in the desired area longer |
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Term
What class controlled substance is butorphanol? |
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Definition
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Term
What class controlled substance is fentanyl? |
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Definition
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|
Term
By what routes is Adequan administered? |
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Definition
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|
Term
What side-effects are associated with opioid administration? |
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Definition
Respiratory depression, addiction, sedation |
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Term
What problems are specifically seen in cats? |
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Definition
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|
Term
Why are glucocorticoids considered better anti-inflammatory agents the NSAIDs? |
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Definition
They act earlier in the inflammatory cycle |
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Term
Which has more potential side-effects, glucocorticoids or NSAIDS? |
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Definition
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Term
A cat suffering from megacolon, a condition which causes profound constipation, may have what prescribed in an effort to stimulate gastrointestinal motility? |
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Definition
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Term
Spike ingested his owner's cardiac medication about half an hour ago. The veterinarian instructs you to give him an emetic that may be administered into the conjunctival sac, then flushed as necessary. The name of that drug is? |
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Definition
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Term
A coating agent that forms an ulcer-adherent complex at the ulcer site is? |
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Definition
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Term
Fleet (sodium phosphate) enemas are contraindicated in what species? |
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Definition
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Term
The group of drugs that is the treatment of choice (at least the strongest) to treat diarrhea in dogs is? |
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Definition
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Term
Which drug is most likely to prevent motion sickness? |
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Definition
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Term
The emetic of choice in cats is? |
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Definition
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Term
The emetic of choice in dogs is? |
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Definition
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Term
Kaolin and pectin (Kaopectate) and bismuth subsalicylate (Pepto-Bismol) are examples of? |
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Definition
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Term
Psyllium and Metamucil are examples of? |
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Definition
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Term
Potential side-effects of the phenothiazine antiemetics include all of the following, except? |
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Definition
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Term
A stool softener often helpful in patients recovering from anal surgery is? |
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Definition
Docusate sodium succinate (DSS, Colace) |
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Term
By what route is insulin usually administered in cases of uncomplicated diabetes? |
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Definition
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Term
Most anti-ulcer medications are? |
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Definition
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Term
Common side-effects of chemotherapeutic drugs include all of the following except? |
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Definition
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Term
Sterile hemorrhagic cystitis is associated with toxicity from what chemotherapeutic agents? |
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Definition
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Term
A chemotherapy drug known for its ability to cause irreversible dilated cardiomyopathy in canine patients is? |
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Definition
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Term
It is extremely important to prevent perivascular injection of which two chemotherapeutic agents? |
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Definition
Methotrexate and vincristine (Oncovin) |
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Term
T/F--Oxymorphone causes nephrotoxicity. |
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Definition
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Term
T/F--Ivermectin has an immunosuppressive effect. |
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Definition
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Term
T/F--In multi-drug chemotherapeutic protocols, drugs are usually selected that work in different parts of the cell cycle. |
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Definition
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Term
The classic side effected associated with cyclophosphamide (Cytoxan) administration in animals undergoing chemotherapy is? |
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Definition
Sterile hemorrhagic cystitis |
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Term
A cat diagnosed with hyperthyroidism may be offered what three treatments? |
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Definition
1) Radioactive iodine-131 treatment 2) Methimazole (Tapazole) medical management 3) Thyroidectomy surgery |
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Term
What insulin provides the longest duration of action? |
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Definition
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Term
|
Definition
A drug that causes tissue damage when given extravascularly |
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Term
Serious potential side-effects of estrogen administration include? |
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Definition
Bone marrow suppression and pyometra |
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Term
Regu-mate and Synchro-mate-B, used for estrus synchronization in femal animals, are both examples of synthetic... |
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Definition
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Term
Resuspension of NPH insulin is done by? |
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Definition
Gently rolling the bottle |
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Term
The primary function of insulins is to? |
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Definition
Facilitate the entry of glucose into cells |
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Term
Insulin concentration is measured in? |
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Definition
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Term
What short-acting insulin would be chosen to treat an emergency case of diabetic ketoacidosis? |
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Definition
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Term
When diethylstilbestrol (DES), a synthetic estrogen, is used in higher doses it can have the potentially dangerous side effect of? |
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Definition
Bone marrow suppression/anemia |
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Term
Erythropoietin (Epogen) is primarily used in what case? |
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Definition
Cats with chronic renal failure |
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Term
What drug is used to decrease gastric acid production by blocking histamine receptors in the stomach? |
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Definition
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Term
What drug is considered to be a biologic response modifier? |
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Definition
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|
Term
What drug in contraindicated in the treatment of glaucoma? |
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Definition
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|
Term
What chemotherapeutic drug should always be administered in conjunction with saline diuresis? |
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Definition
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Term
What would be prescribed to a cat that has suffered a thromboembolism secondary to hypertrophic cardiomyopathy for its fibinolytic action? |
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Definition
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Term
Oral hypoglycemic drugs, such as glipizide (Glucotrol) are used to treat? |
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Definition
Non-insulin dependent diabetes |
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Term
A veterinarian prescribes erythropoietin for use in a dog with terminal renal failure. Why? |
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Definition
For its ability to stimulate red blood cell production and release |
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|
Term
The most widely used antiemetics in veterinary medicine are the? |
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Definition
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|
Term
What side effect is commonly seen with many chemotherapeutic agents? |
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Definition
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|
Term
|
Definition
constriction of the pupil |
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|
Term
What does CRTZ stand for? |
|
Definition
Chemoreceptor trigger zone |
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|
Term
What hormones are released by the adrenal cortex and what is their function? What areas do they come from? |
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Definition
Zona fasciculata: Glucocorticoids (Cortisol); increases protein and fat breakdown; increased glucose production; inhibits immune response Zona glomerulosa: Mineralocorticoids (Aldosterone); increased sodium ion reabsorption; potassium and hydrogen ion excretion Zona reticularis: Androgens; minor importance in males; in females development of some secondary sexual characteristics |
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Term
What hormone released from the pituitary gland stimulates hormone production by the adrenal gland? |
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Definition
Adrenocorticotropic hormone (ACTH) |
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|
Term
What is Cushing's disease? |
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Definition
Characterized by the hyper-secretion of cortisol and androgens and possibly by excess aldosterone production |
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|
Term
What are the classic symptoms of Cushing's disease? |
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Definition
PU/PD; abdominal distention; muscle weakness; thin skin; symmetrical alopecia; reproductive problems |
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|
Term
What are the three possible causes of Cushing's disease? |
|
Definition
1) Pituitary tumor 2) Adrenal gland tumor 3) Iatrogenic caused by excessive use of steroids |
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|
Term
What is Addison's disease? |
|
Definition
Characterized by abnormally low levels of aldosterone and cortisol. |
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|
Term
What symptons can be seen with Addison's? |
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Definition
Weakness, weight loss, fatigue, anorexia, increased skin pigment |
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Term
What changes in electrolytes may be seen in an animal with Addison's and why do these changes occur? |
|
Definition
Decreased aldosterone inhibits sodium reabsorption causing low sodium and increased potassium also due to low aldosterone. |
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|
Term
What change may be seen on an ECG in Addison's disease? |
|
Definition
T-waves will be big and spikey |
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|
Term
What are some things glucocorticoids can be used to treat? |
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Definition
1) Allergic reactions/conditions 2) Inflammation of the musculoskeletal system 3) Shock/toxemia 4) Laminitis 5) Occular inflammation 6) Addison's disease 7) Autoimmune disease 8) Lymphocytic neoplasms |
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|
Term
How should glucocorticoids be dosed differently between dogs and cats? |
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Definition
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|
Term
Why is it best to wean animals off of glucocorticoids slowly? |
|
Definition
By tapering off slowly it gives the body a chance to resume natural steroid production helping prevent Iatrogenic Addison's disease. |
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|
Term
How should glucocorticoids be administered to minimize side-effects? |
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Definition
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|
Term
Explain the basic mechanism by which NSAIDS work to decrease inflammation. |
|
Definition
They inhibit an enzyme called cyclooxygenase prohibiting the formation of prostaglandins that cause inflammation. |
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Term
What is the difference between the way opioids control pain and the function of NSAIDS? |
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Definition
NSAIDS control pain by controlling inflammation while opioids control pain by binding with specific receptor sites in the brain, spinal cord and peripheral tissue blocking or inhibiting pain impulses to higher CNS centers resposible for the perception of pain. |
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Term
Opioid agonists are what schedule of controlled drug? Give some examples. |
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Definition
CII; codeine, morphine, fentanyl, hydromorphone |
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|
Term
What is the most commonly used opioid agonist/antagonist? What schedule controlled drug is it? |
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Definition
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|
Term
Purpose of periosteal elevator? |
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Definition
To lift up the periosteum or push soft tissue away from the bone. |
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Term
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Definition
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|
Term
|
Definition
To remove or break up small chuncks of bone or cartilage; named differently based on the shape of the handles |
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|
Term
|
Definition
To cut through or shape bone as it is hit by a bone mallet |
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|
Term
If an osteotome has a curved blade then it is called a? |
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Definition
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|
Term
Purpose of a bone mallet? |
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Definition
To set intramedullary pins or strike an osteotome. |
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|
Term
Describe a trephine. What is it used for? |
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Definition
Small cutting blades to drill into the bone-stylet and hollow core (cross-shaped); to perform bone biopsies or to drill small holes into the skull or sinus |
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|
Term
Purpose of Kern Bone holding forceps? |
|
Definition
To hold bone fragments together for fixation with pins, screws, or plates |
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|
Term
Purpose of bone chuck? Also called? |
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Definition
To place intramedullary pins; Intramedullary pin chuck |
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|
Term
Kirschner-Ehmer apparatus does what? |
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Definition
Provides external fixation for fractures |
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Term
Purpose of a bone curette? |
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Definition
To scrape out cancellous bone from the medullary cavity or cartilage in an OCD lesion |
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Term
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Definition
Osteochondritis (osteochondrosis) Dessicans; an abnormality in cartilage development which occurs at an articular surface, such that a cartilage flap arises |
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Term
What two places are most often affected by OCD? |
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Definition
1) Head of the humerus in the shoulder 2) Humeral condyle in the elbow |
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Term
What are the three types of open fractures? |
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Definition
Grade I: small puncture through the skin; bone was exposed to the outside, but is no longer visible Grade II: larger puncture or tear in the skin around the location of the fracture with more soft tissue damage associated with external trauma Grade III: open fracture with large tears in the skin, with loss of skin. So much skin is lost that the bone is still exposed. Can be called "shearing injuries" |
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Term
What are the five types of fracture classifications? |
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Definition
1)Bone fractured 2) Open or closed: open fractures penetrate the skin 3) Location of the fracture (midshaft, articular, etc.) 4) Type of fracture (oblique, transverse, spiral) 5) Reducible or non-reducible |
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