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Plague
26
Agriculture
Undergraduate 2
11/12/2012

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Term
What are different names for plague?
Definition
Plague
Black death
Bubonic plague
Yersiniosis
Term
What is the name for the bacteria that causes plague?
Definition
Yersinia Pestis
Term
What are some characteristics of Yersinia Pestis?
Definition
Gram negative
Non-spore forming
small bacteria
clothes pin shaped
Term
What destroys yersinia pestis? What is the survival rate?
Definition
It is destroyed by sunlight and desiccation.
Survives 1 hour in air, briefly in soil, 1 week in soft tissue, years when frozen
Term
Where is plague thought to have originated?
Definition
In Central Asia or Africa and spread to different continents through ships
Term
What are the three documented cases of old world plague?
Definition
~Justinian plague
~Black death (europe)
~China (continues today)
Term
Who discovered the agent of plague? When?
Definition
~Alexander Yersin in 1894
~Dr Kitasato discovered the bacteria but stained it wrong.
Term
How is plague maintained in every continent except australia and antarctica?
Definition
Through wild rodent populations in semiarid areas.
Term
If you're a wildlife biologist what area in the US should you be aware of?
Definition
The southwestern part because it has plague
Term
Where is the plague found in the US?
Definition
In the West but it is slowly moving to the east.
Term
What is the vector for plague?
Definition
Fleas
Term
How is transmitted using the flea?
Definition
After a flea ingests blood from an infected animal, the bacteria replicate in the flea gut. The digestive tract is then blocked and affects swallowing. The flea then starves and tries to eat which results in regurgitation of the bacteria back into the host.
Term
Where was the first reported case of plague in north America?
Definition
In San Francisco in 1900s
Term
When plague first arrived in california, what other animal was effected?
Definition
California Ground Squirrels
Term
How is plague usually transmitted?
Definition
Through the bite of a flea, ingestion of infected carcasses, aerosol
Term
What are reservoir hosts in plague?
Definition
~do not suffer 100% mortality from plague
~example:rats
Term
What are amplification rodent hosts?
Definition
~These species have a high mortality and high population density
~example: ground squirrels
Term
What are Resistant Non-rodent plague hosts?
Definition
Ungulates and rodent consuming carnivores
~example:felines
Term
What are susceptible non-rodent plague hosts?
Definition
High morbidity and mortality when infected
~example: Man, domestic cats, wild cats, mountain lions.
Term
What are the clinical presentations for bubonic plague in man?
Definition
~swelling- can rupture and drain
~cervical axillary lymph nodes are frequently affected
Term
How can plague be diagnosed?
Definition
Gram staining lymph nodes
flourescent antibody tests
PCR (DNA) testing
Surveillance: examination of fleas collected in dens of rodents
-also examination of coyotes that are resistant but sampled for antibodies of bacteria.
Term
Are vaccines available for plague?
Definition
USARMIID
Delta Dust
Term
What is being used to keep prairie dogs from getting plague?
Definition
Cotton balls treated with pyrethrins
insecticidal spraying of dens
Powder infused into dens
Term
What is needed for treatment of plague?
Definition
Rapid diagnosis, antibiotic therapy and if untreated, very high mortality rate (50 for bubonic, 100 for pneumonic and septicemia)
Term
What is a sentinel species for plague?
Definition
A coyote
Term
How is plague studied?
Definition
By capturing fleas, mouse inoculation, prairie dog colony studies
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