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XIII. The Integumentary System
SKIN
42
Anatomy
Undergraduate 2
09/21/2013

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Term
functions of the integumentary system
Definition
protect, physical barrier, chemical brarier, form, maintain hydration (keep water in system), temperature and regulation, vitamin D production, detection of stimuli, blood reservoir, excretion (removal of waste product)
Term
Structure: Layers
Definition
epidermis and dermis...not hypodermis which contains fat
Term
what is the name of epidermis
Definition
thick keratinzied stratified squamos epithelium - protective
Term
what are the 4 cell types of the epidermis
Definition
keratinocytes, melanocytes, langerhand cells, merkel cells
Term
Keratinocytes
Definition
keratin...deep layer MITOTIC, keratin is intermediate filament
Term
melanocyte
Definition
basal layer of epidermis, manufacture protein melanin (transcript and translate), melanin transferred from melanocyte along cytoplasmic projections to neighboring keratinocytes
Term
langerhan cells
Definition
dendritic cells...derived from immune system (white blood cells)

manufactured in bone marrow

Macrophage make way through blood stream of epidermis
Term
merkel cells
Definition
sensory receptor cells, associated with a nerve ending...new epidermis is generated every 35-45 days
Term
What are the trends from deep to superficial
Definition
mitotic -> non mitotic
keratin synthesis -> keratin modified
access to blood supply --> no access
living cells --> non living cells
Term
Epidermis layers from bottom to top
Definition
Stratum germinativum
stratum spinosum
stratum granulosum
stratum lucidum
stratum corneum
Term
stratum germinativum/ basale
Definition
deepest, youngest, mitotic
Term
stratum spinosum
Definition
spiny projections artifact (called prickle cells)
Term
stratum granulosum
Definition
flattened, contains granules, water proofing layer
last cells to be nourished by blood indirectly **
Term
stratum lucidum
Definition
only present in thick skin plams and soles feet
Term
which layer of the epidermis is only found in palms and soles feet
Definition
stratum lucid
Term
stratum corenum
Definition
thickend protective cornified flakes off most superficial
20-30 cell layers thick
Term
2nd layer of integument, what's it made out of and bound together with
Definition
dermis
strong connective tissue layer
bound together with collagen elastin and reticular fibers, synthesized by fibroblasts
Term
Dermis contains which two layers
Definition
papillary layer
reticular layer
Term
papillary layer
Definition
thin-superficial
blood vessles
projections and indentations papillae- projections push up against epidermis

dermal ridges-palms of hands soles and feet...imprint the epidermis causes increase gripping and finger and footprints
Term
Reticular layer made out of what type of tissue
Definition
deep, dense, irregular connective tissue
thicker
collagen bundles (have high tensile strength), binds water, elastin--recoild, striae stretch marks; collagen tearing
Term
Color-pigments
(3)
Definition
melanin
carotene
hemoglobin
Term
melanin
Definition
gives us our skin color, synthesized in melanocyte--protein
freckles and moles concentrations of melanin
Term
carotene
Definition
yellowish; varies with diet--egg yolks and yellow vegetable
Term
hemoglobin
Definition
redness; blood
sick individuals blood vessels constrict; pale
Term
Hair, keratinocytes
Definition
layers of dead cells;keratinocyte
Term
what does hard keratin have
Definition
more compact; sulfur bonds; durable
Term
shaft project from skin--visible
shape of shaft determines shape of hair
Definition
flat-kinky curly
oval- wavy
round-straight and coarse
Term
Shaft projections from skin (hair)
layers
Definition
3 in the shaft
medulla has softest keortin
cortex bulky flat cells
cuticle singl cells maintain integrity of shaft and keep each shaft separate from e/o
Term
root of the hair is embedded in skin and is visible. true or false.
Definition
false, root of the hair is embedded in skin and is NOT visible
Term
color determined by melanocytes at the base of follicle where is it transferred
Definition
to cortex/cortical cells
Term
Hair follicle
Definition
shaft extend to dermis/hypodermis
1)hair bulb- growth @ matrix
2)root hair plexus- nerve
3)papillae-blood supply, and lies deep to matrix
Term
arrector pili muscle
Definition
attached to hair shaft causes goose bumps
contracts when scared/cold
made out of CT smooth muscle
Term
Nails
what is hard keratin made out of (layer of epidermis)
what is nail matrix made out of
Definition
modification of existing epidermis
a)Hard keratin- stratum corneum; tough surface (tough surface)
b)nail matrix- stratum germinativum of the epidermis
Term
Glands (3)
2 special sweat glands
Definition
eccrine, apocrine, sebaceous, ceruminous, mammary
Term
function of sweat
Definition
temperature regulation
Term
eccrine (merocrine)
Definition
coiled, tubular, open on much of body but concentrated in skin of palms forehead soles of feet

sweat is formed as a filtrate of blood
Term
sweat is controlled by
Definition
the sympathetic nervous system
Term
sweatpasses through

it contains
Definition
secretory cells of the glands and fluid is released by exocytosis
contains water, NACl, som vitamin C, antibodies, antimicrobials, and metabolic wastes ph=4-6
Term
apocrine
Definition
also merocrine gland but located in axillary and anogenital regions
larger than eccrine and DUCTS EMPTY INTO HAIR FOLLICLES
Term
Apocrine characteristic
Definition
secrete sweat, fat, and proteins
odorless- bacteria on skin cause body odor
begin function at puberty
not involved in temperature regulation
sympathetic control
Term
ceruminous
mammary gland
Definition
wax producing external ear canal
secrete milk
Term
sebaceous gland/alveolar holocrine gland
Definition
oil gland
located everywhere but palms of hands and soles of feet
OUTGROWHTS OF HAIR FOLLICLES
secrete sebum: accumulate oily lipids then burst
hormonal stimulation acne- staph infections treated with antibiotic
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