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Zoonoses, Bioterrorism, Regulatory Med
JJC Vet Tech LAN
116
Veterinary Medicine
Undergraduate 1
12/16/2013

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Cards

Term
Microbe/s that cause/s Bangers?
Definition
Brucella abortus (everything)
Brucella melitensis (mostly goats)
Brucella ovis (sheep)
Brucella canis (K9)
Brucella suis (mostly swine)
Term
If an animal is positive for Brucellosis, what happens to that animal?
Definition
-often culled
-meat can still be eaten if well-cooked, so brand a "B" onto animal's R jaw
Term
Colloquial names for Brucellosis in:
-cattle
-equine
-swine/sheep/goats/k9
-humans
Definition
-Cattle: "Bangs Disease," "Bangers," "Contagious Abortion"
-Equine: "Fistulous Withers"
-Swine/sheep/goats/k9: Brucellosis
-Humans: "Undulant Fever," "Malta Fever"
Term
Symptoms of Bangers?
Definition
-abortion
-males get orchitis/epididymitis
Term
orchitis
Definition
swelling of testicles that resembles cancer
Term
How is Brucellosis spread?
Definition
-ingestion of placenta, milk, fetus
-semen, vaginal discharge
-conjunctival contamination
-wild carnivores can spread long distances
Term
Symptoms of Brucellosis in humans?
Definition
-"undulant fever" means it cycles between vary high and then low
Term
How can people contract Brucellosis?
Definition
-eating contaminated meat that isn't cooked well enough
-drinking contaminated raw milk
-in the past, vets would clean out retained placenta without gloves
Term
Which zoonoses is the US now free of?
Definition
-Brucellosis
-Psuedorabies
Term
What species primarily gets Brucella melitensis?
Definition
goats
Term
How is Brucella canis spread?
Definition
coitus
Term
Symptoms of Brucella canis?
Definition
-abortion, then female gets very ill
Term
Why are chickens no longer allowed to "follow up" on pigs?
Definition
-some chickens have Mycobacterium avium
-pigs eat dead chickens, get tuberculosis
Term
What is the body's response to Mycobacterium bovis?
Definition
-can't destroy the bacterium, so it forms scar tissue around it = buboes
-rad of lungs looks like polka dots
Term
Microbe that causes tuberculosis?
Definition
Mycobacterium bovis
M. avium
M. johnei
Term
3 R's of Bioterrorism?
Definition
-recognize
-report
-respond
Term
How do cattle contract tuberculosis?
Definition
inhale/ingest bacteria in sputum
Term
How do cattle spread TB?
Definition
sputum, infected meat, infected milk
Term
How to perform a TB test?
Definition
- Inject 0.1cc Tuberculin ID into tail fold
- Read 72 hrs later - compare to pea
Term
How many cows can you test for TB with one TB syringe?
Definition
10 - each gets 0.1cc
Term
Who can perform a TB test?
Definition
accredited vet (vs licensed vet)
Term
What species get M. bovis?
Definition
-cows
-swine
-humans
-poultry
-feline / k9
-goats
-sheep
Term
What species get M. avium?
Definition
-poultry, but ingesting/inhaling sputum
-swine by ingestion of poultry or by-products
Term
What species get M. johnei?
Definition
-cattle
Term
Name the disease caused by Mycobacterium johnei.
Definition
Johne's Disease (pronounced "yo-knees")
Term
How do calves get Johne's?
Definition
-ingest feces or colostrum
Term
How to best control Johne's?
Definition
-strict isolation of neonates
-pasteurized colostrum
Term
Symptoms of Johne's?
Definition
-chronic weight loss
-diarrhea because rectal mucosa scar over and can't absorb water
Term
What microbe causes k9 coccidiosis?
Definition
Neospora caninum
Term
What species get Neospora caninum? How are they infected?
Definition
-k9: ingest oocyte/spore from aborted calves
-bovine: k9 feces in feedstuffs/water/pasture; placental transfer
Term
3 outcomes of fetus infected with Neospora caninum:
Definition
1- abortion
2- born but quickly dies
3- neonate survives, no carrier state
Term
Which zoonosis is the US getting under control?
Definition
Neospora caninum
Term
Which zoonosis is rampant in livestock?
Definition
Lepsporosis
Term
What animals can get Lepto?
Definition
-cattle, sheep, goats, horses, pigs
-humans
-k9, feline
Term
How is Lepto spread?
Definition
-urine is ingested or contaminates conjunctiva
Term
What farm workers are at risk of getting Lepto, and why?
Definition
-milkers in milk pits
-urine splashes into their eye and conjunctiva
Term
What species of Lepto can cattle get?
Definition
all of them
Term
What animals get Leptospira grippotyphosa?
Definition
-cattle
-dogs
Term
What animals get Leptospira hardjo?
Definition
-cattle
Term
What species of Leptospira can humans get?
Definition
-L. pomona
-L. icterohaemorrhagiae
-L. canicola (?maybe)
Term
What is scrapie?
Definition
prion disease of sheep and goats
Term
How is scrapie contracted?
Definition
-ingestion of fetal/placental juices
-contamination of scarified skin by prion
Term
BSE
Definition
Bovine Spongiform Encephalitis = Mad Cow
Term
PRRS
Definition
Porcine Respiratory and Reproductive Disease
Term
TGE
Definition
Transmissable Gastroenteritis (swine)
Term
PRV
Definition
Pseudorabies Virus
Term
Other names for Pseudorabies?
Definition
PRV, Mad Itch, Aujeszky's Disease
Term
What animals get pseudorabies?
Definition
-mostly pigs
-also k9, feline, sheep, cattle
Term
Symptoms of pseudorabies?
Definition
-virus replicates under skin causing intense itching
-pig/animal kills itself trying to scratch the itch
Term
In 2000, Great Britain found that over __% of (what animal by-product?) was contaminated with anthrax.
Definition
over 50% of bone meal imported into G.B.
Term
What diseases were discussed in class as being potential bioterrorism agents?
Definition
-anthrax
-Foot and Mouth
-Rinderpest
-African Swine Fever
-Hog Cholera/Swine Fever
Term
What microbe causes anthrax?
Definition
Bacillus anthracis
Term
What kind of bacterium is B. anthracis?
Definition
anaerobic, spore-forming
Term
How are grazing animals infected with anthrax?
Definition
ingesting contaminated soil or forage
Term
Mechanical vectors of anthrax?
Definition
-hay mite moves spores from contaminated forage to confined animals

-carrion eaters
Term
Areas of the US where anthrax is endemic are called __ __. What can't take place in these spots?
Definition
-anthrax belts
-grazing, planting, or harvesting
Term
States mentioned in class that have endemic anthrax?
Definition
TX, OK
Term
How can anthrax be spread?
Definition
-hay mite
-flooding
-bone meal
-inhalation/ingestion of spores
-spores in wound
-grazing
-harvesting
Term
What does anthrax look like under the microscope?
Definition
purple (Gm+) chains of rods
Term
What disease did anthrax used to cause in humans in the 1930s?
Definition
Wool Sorters Disease
Term
How do anthrax-infected animals shed the bacterium?
Definition
-feces
-blood
-tissues
Term
What NOT to do with a carcass you suspect has anthrax:
Definition
DO NOT OPEN IT!!!
Term
How to collect samples from a suspect anthrax carcass?
Definition
-needle, amputated tail or ear

*wear a mask or Hazmat suit!!!**
Term
Anthrax prevents what from happening in the body?
Definition
prevents blood from clotting
Term
What should you do with the carcass of an anthrax+ animal?
Definition
"Burn or Bury"

-if burying, cover with lime and pack down soil
Term
Symptoms of TGE?
Definition
-bloody diarrhea that leads to death
Term
What causes foot rot?
Definition
-Fusobacterium necrophorum
-Bacteroides melaninogenicus
Term
Another term for foot rot?
Definition
necrotic pododermatitis
Term
Polioencephalomalacia is caused by what?
Definition
thiamine deficiency
Term
Another name for pinkeye in cows?
Definition
Infectious Bovine Keratoconjunctivitis
Term
How is pinkeye in cattle spread?
Definition
facefly Musca autumnalis spreads the bacterium Moraxella bovis
Term
Symptoms of PRRS?
Definition
-small litters (absorb fetus)
-infertility
-death

*possibility at the farm we visited?
Term
What is metritis? (not a typo for mastitis)
Definition
inflammation of the uterus
Term
MMA
Definition
mastitis, metritis, agalactia
Term
agalactia
Definition
no milk production
Term
What animal gets MMA?
Definition
sows
Term
In Dr. Stein's story about the young couple who had a pig farm, what disease did their pigs end up having? How did they get it?
Definition
-TGE (transmissible gastroenteritis)
-tires on feed delivery truck
Term
Other names for Foot and Mouth Disease?
Definition
FMD, "Aphthous Fever"
Term
What animals can get FMD?
Definition
cattle and swine
Term
Which non-zoonotic diseases is the US free of?
Definition
-Foot and Mouth since the 1920s
-Hog Cholera
Term
What sort of microbe causes FMD?
Definition
virus
Term
How do animals contract FMD?
Definition
inhale/ingest virus
Term
Early signs of FMD?
Definition
oropharyngeal infection within days of infection
Term
Classic signs of FMD?
Definition
-tongue, lip, gum, coronary band lesions
-thick, ropey saliva
Term
How is FMD spread?
Definition
-thick, ropey saliva contaminates everything
-all meat and tissue products
Term
What is "swill"?
Definition
prohibited substances that are not supposed to be fed to livestock
Term
What is the coronary band?
Definition
area where hoof meets skin
Term
morbidity
Definition
# infected
Term
mortality
Definition
# who die from infection
Term
Mortality of FMD?
Definition
100% if not nursed heavily - mouth ulcers take 4-6mo to heal
Term
What to do in event of FMD outbreak?
Definition
cull every single animal, whether or not it's infected
Term
Rinderpest
Definition
viral disease of ruminants currently confined to Central/South America, Africa
Term
African Swine Fever
Definition
viral disease of swine currently confined to Africa
Term
Hog Cholera
Definition
-viral disease of swine
-causes debilitating losses
Term
Symptoms of Hog Cholera?
Definition
-106-108 fever
-large purple skin blotches on abdomen
Term
Primary route of infection of Hog Cholera to naive swine?
Definition
feeding pork scraps and tissues from infected swine
Term
Cervidae
Definition
deer, elk, moose, caribou, reindeer, red deer (wapiti)
Term
IL considers livestock to include:
Definition
cattle, goats, bison, Cervidae, ratites, horses, swine, sheep, poultry
Term
ratites
Definition
emus, kiwis, cassowaries, rheas, ostriches
Term
What animals do not have any health requirements to be imported into IL?
Definition
-llamas
-antelope
-hedgehog
-cat
Term
What livestock animals are affected by scabies? What mite causes this?
Definition
-cattle and sheep
-Psoroptes
Term
Is TB zoonotic?
Definition
Humans can't get it from animals, but humans easily transmit it to animals.
Term
Brucellosis tests
Definition
plate, tube, card (usu. agglutination)
Term
Pseudorabies tests
Definition
ELISA, SN, Latex
Term
EIA test
Definition
Coggins
Term
What ID must all cattle have in regards to Brucellosis?
Definition
metal ear tag - Bangs tag
Term
What 3 diseases are tested for when importing livestock into IL?
Definition
Brucellosis, PRV/Pseudorabies, TB
Term
Indications of a possible bio-warfare attack:
Definition
-unusual disease entity for area or unusual combos of disease
-apparent aerosol transmission
-high morbidity/mortality
-sentinel dead animals of multiple species
...others on handout
Term
Possible bacterial biowarfare agents:
Definition
-anthrax
-tularemia
-plague
-Brucellosis
-Q fever
Term
Possible viral biowarfare agents:
Definition
-smallpox
-equine encephalitis
-hemorrhagic fevers
-FMD
Term
Possible toxins as biowarfare agents:
Definition
-Staph enterotoxin B
-Ricin
-Botulinum toxins
-Trichothecene mycotoxins
Term
RB51
Definition
new Brucellosis vaccine for heifers/cows- the old one could infect humans via needle stick
Term
CVI
Definition
Certificate of Vet Inspection
Term
cosignor / cosignee
Definition
cosignor = owner/seller
cosignee = buyer
Term
What form do pets need to fly on a plane?
Definition
Health Certificate for Pets
Term
Symptoms of anthrax?
Definition
Pulmonary form:
-cold-like at first
-dyspnea -> shock

Cutaneous form:
-raised bump at first
-ulcers, necrosis
-acute death / bleeding from orifices

Intestinal form:
-V/D
-abdominal pain
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