Term
Hydrogenation of Benzene
[image] |
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Definition
| C6H6 + H2,catalyst→ C6H12 |
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Term
Electrophilic Aromatic Substitution
Chlorination and Bromination |
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Definition
C6H6 + X2,FeX2 → C6H5X + HX
X = Cl, Br
FeX2 is a catalyst |
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Term
Electrophilic Aromatic Substitution
Nitration |
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Definition
| C6H6 + HNO3, H2SO4 → C6H5NO3 + H2O |
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Term
Electrophilic Substitution
Sulfonation |
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Definition
C6H6 + SO3, H2SO4 → C6H5SO3H
(reversible) |
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Term
Friedel-Crafts Alkylation
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Definition
C6H6 + RX + AlCl3 → C6H5R + HX
(R+ is subject to carbocation rearrangement) |
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Term
Friedel-Crafts Alkylation
Intermolecular |
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Definition
C6H5-(CH2)4-Cl + AlCl3 → C6H4-C4H8 + HCl
C6H4-C4H8 = benzene ring attached by
a whole side to a cyclohexane ring |
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Term
Friedel-Crafts Alkylation
Alcohol Substrate |
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Definition
| C6H6 + RC(OH)HR' + BF3, 60°C → C6H5-C(R)HCH3 +H2O |
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Term
Friedel-Crafts Alkanoylation
Alkanoyl Halides |
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Definition
| C6H6 + RC(O)Cl + 1.AlCl3 2.H2O → C6H5-C(O)R + HCl |
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Term
Friedel-Crafts Alkanoylation
Anhydrides |
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Definition
| C6H6 + CH3C(O)OC(O)CH3 + 1.AlCl3 2.H2O → C6H5-C(O)CH3 + CH3COOH |
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Term
| Radical Allylic Halogenations |
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Definition
| RCH2CH=CH2 + NBS,CCl4,hv → RC(Br)HCH=CH2 + RCH=CHCH2Br |
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Term
| Sn2 Reactivity of Allylic Halides |
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Definition
| CH2=CHCH2X + Nu:- + acetone (CH3)2C=O → CH2=CHCH2Nu + X- |
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Term
| Allylic Grignard Reagents |
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Definition
| CH2=CHCH2BR + Mg, ether → CH2=CHCH2MgBr |
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Term
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Definition
| RCH2CH=CH2 + tMEDA → RC:-HCH=CH2 Li+ |
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Term
| Alkylation of Alkynyl Anions |
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Definition
RCΞCH + 1.NaNH2, liquid NH3 2.R'X → RCΞCR'
Sn2 reaction, R' must be a primary alkane |
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Term
| Alkylation with Oxacyclopropane |
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Definition
RCΞCH +
1.RLi, THF 2.cyclo (CH2)2O 3.H+, H2O
→
RCΞCCH2CH2OH
attack takes place at the less substituted on unsymmetrical oxacyclopropanes |
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Term
| Alkylation with Carbonyl Compounds |
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Definition
RCΞCH +
1.RLi, THF 2.R'(C=O)R" 3.H+, H2O
→
RCΞCC(OH)(R)(R') |
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Term
| Reduction of an Alkyne to get a trans-Alkene |
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Definition
RCΞCR + 1.2Na, liquid NH3 2.H+,H2O → HRC=CHR
radical 4 step mechanism |
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